MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals (Q34721752)

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scientific article published in January 2011

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English	MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals	scientific article published in January 2011

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scholarly article

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19 January 2020

MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals (English)

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19 January 2020

rhabdomyosarcoma

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Francesco Marampon

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19 January 2020

Giovanni Luca Gravina

2

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19 January 2020

Carmela Ciccarelli Priori

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19 January 2020

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19 January 2020

Richard Pestell

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Richard G Pestell

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19 January 2020

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Agnese Di Rocco

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19 January 2020

Pierluigi Bonfili

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19 January 2020

Mario Di Staso

5

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19 January 2020

Caterina Fardella

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19 January 2020

Lorella Polidoro

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19 January 2020

Claudio Festuccia

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19 January 2020

Vladimir M Popov

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19 January 2020

Vincenzo Tombolini

12

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19 January 2020

publication date

1 January 2011

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19 January 2020

Molecular Cancer Therapeutics

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19 January 2020

10

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19 January 2020

1

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19 January 2020

159-168

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19 January 2020

Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

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The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts

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RAS signaling dysregulation in human embryonal Rhabdomyosarcoma

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7 July 2018

MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

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7 July 2018

Cyclin D1 in low-dose radiation-induced adaptive resistance.

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DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

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Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB

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ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program

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Tumor cell radiosensitivity is a major determinant of tumor response to radiation

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7 July 2018

Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.

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Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair.

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MAPK signal specificity: the right place at the right time

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Transcriptional regulation and transformation by Myc proteins

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Getting at MYC through RAS.

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Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells

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Protein measurement with the Folin phenol reagent

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Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution

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Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial

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7 July 2018

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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7 July 2018

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

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Role of radiation therapy in parameningeal rhabdomyosarcoma

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Cyclin D1 overexpression enhances radiation-induced apoptosis and radiosensitivity in a breast tumor cell line

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12 December 2020

based on heuristic

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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

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12 December 2020

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Sustained loss of a neoplastic phenotype by brief inactivation of MYC

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12 December 2020

based on heuristic

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10.1158/1535-7163.MCT-10-0631

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19 January 2020

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19 January 2020

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19 January 2020

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