Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration (Q34701955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20505194%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration (English)

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3 February 2020

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0 references

1 reference

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3 February 2020

Timothy W Olsen

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3 February 2020

Curtis L Nordgaard

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3 February 2020

author name string

Pabalu P Karunadharma

series ordinal

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3 February 2020

language of work or name

English

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publication date

26 May 2010

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Investigative Ophthalmology Visual Science

3 February 2020

published in

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3 February 2020

volume

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3 February 2020

issue

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3 February 2020

page(s)

5470-5479

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Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes

3 February 2020

cites work

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7 July 2018

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Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration

7 July 2018

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Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration

7 July 2018

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Quantification of the mitochondrial DNA common deletion in presbycusis

7 July 2018

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Mitochondrial DNA damage and its potential role in retinal degeneration

7 July 2018

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Variations in mitochondrial DNA copy numbers in MS brains

7 July 2018

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The 4977 bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: a useful biomarker or more?

7 July 2018

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Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid

7 July 2018

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Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration

7 July 2018

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What causes mitochondrial DNA deletions in human cells?

7 July 2018

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Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration

7 July 2018

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Absolute quantitation of a heteroplasmic mitochondrial DNA deletion using a multiplex three-primer real-time PCR assay

7 July 2018

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Ranibizumab versus verteporfin for neovascular age-related macular degeneration.

7 July 2018

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Ranibizumab for neovascular age-related macular degeneration

7 July 2018

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The proteome of central and peripheral retina with progression of age-related macular degeneration.

7 July 2018

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

7 July 2018

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Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration

7 July 2018

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The retinal pigment epithelium in visual function

7 July 2018

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Decline in skeletal muscle mitochondrial function with aging in humans

7 July 2018

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Declines in arrestin and rhodopsin in the macula with progression of age-related macular degeneration

7 July 2018

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The Minnesota Grading System of eye bank eyes for age-related macular degeneration

7 July 2018

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Prevalence of age-related macular degeneration in the United States

7 July 2018

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Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

7 July 2018

1 reference

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Relative susceptibilities of mitochondrial and nuclear DNA to damage induced by hydrogen peroxide in two mouse germ cell lines

7 July 2018

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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

7 July 2018

1 reference

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Oxidative damage to mitochondrial DNA and its relationship to ageing

7 July 2018

1 reference

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Reactions of oxyl radicals with DNA.

7 July 2018

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Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay

7 July 2018

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Analysis of oxidative damage by gene-specific quantitative PCR.

7 July 2018

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Mitochondrial DNA oxidative damage triggering mitochondrial dysfunction and apoptosis in high glucose-induced HRECs

26 October 2018

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Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration

26 October 2018

1 reference

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Quantitative change in mitochondrial DNA content in various mouse tissues during aging

26 October 2018

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Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover

26 October 2018

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Measuring oxidative mtDNA damage and repair using quantitative PCR.

26 October 2018

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26 October 2018

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Mitochondrial abnormalities in ageing macular photoreceptors.

26 October 2018

1 reference

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Hydrogen peroxide stimulates apoptosis in cultured human retinal pigment epithelial cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061495

Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061495

Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart

26 October 2018

1 reference

12 December 2020

The burden of age-related macular degeneration: a value-based analysis

1 reference

12 December 2020

Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction

1 reference

12 December 2020

Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy

1 reference

12 December 2020

Accumulation of mitochondrial DNA deletions in human retina during aging

1 reference

12 December 2020

Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells

1 reference

12 December 2020

Mitochondrial DNA haplogroups and age-related maculopathy

1 reference

12 December 2020

The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy

1 reference

12 December 2020

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells

1 reference

12 December 2020

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.10-5429

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20505194%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20505194%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

20505194

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20505194%20AND%20SRC:MED&resulttype=core&format=json