Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes (Q34665492)

3 August 2017

title

Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes (English)

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3 August 2017

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1 reference

Sabine Tejpar

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Brian M Bot

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Thomas C Smyrk

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3 August 2017

Justin Guinney

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3 August 2017

Steven R Alberts

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3 August 2017

Michelle Mahoney

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3 August 2017

Frank A Sinicrope

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3 August 2017

Qian Shi

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3 August 2017

Stephen N Thibodeau

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3 August 2017

Rodrigo Dienstmann

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3 August 2017

Mauro Delorenzi

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3 August 2017

Richard M Goldberg

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3 August 2017

Daniel J Sargent

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3 August 2017

language of work or name

English

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publication date

8 October 2014

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3 August 2017

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3 August 2017

volume

148

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3 August 2017

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3 August 2017

page(s)

88-99

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Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer

3 August 2017

cites work

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Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy

7 July 2018

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A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.

7 July 2018

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Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women

7 July 2018

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Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

7 July 2018

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Genomic aberrations occurring in subsets of serrated colorectal lesions but not conventional adenomas

7 July 2018

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KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers

7 July 2018

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Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers

7 July 2018

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Mutation profiling and microsatellite instability in stage II and III colon cancer: an assessment of their prognostic and oxaliplatin predictive value

7 July 2018

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BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics

7 July 2018

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Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers

7 July 2018

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Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial

7 July 2018

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EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

7 July 2018

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Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications

7 July 2018

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

7 July 2018

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Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803

7 July 2018

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Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution

7 July 2018

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Oxaliplatin as adjuvant therapy for colon cancer: updated results of NSABP C-07 trial, including survival and subset analyses

7 July 2018

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DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

7 July 2018

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V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a

7 July 2018

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Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

7 July 2018

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Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

7 July 2018

1 reference

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Role of the serrated pathway in colorectal cancer pathogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Microsatellite instability in colorectal cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

7 July 2018

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Genomic and epigenetic instability in colorectal cancer pathogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: results from NSABP C-07.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Systematic review of microsatellite instability and colorectal cancer prognosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Mutations of the BRAF gene in human cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Morphology of sporadic colorectal cancer with DNA replication errors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

RAF/RAS oncogenes and mismatch-repair status

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274188

Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25305506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25305506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25305506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1053/J.GASTRO.2014.09.041

1 reference

3 August 2017

1 reference

3 August 2017

1 reference