The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation? (Q34652193)

3 August 2017

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title

The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation? (English)

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3 August 2017

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Sathiya N Ramakrishnan

series ordinal

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3 August 2017

George E O Muscat

series ordinal

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3 August 2017

publication date

28 April 2006

1 reference

Nuclear Receptor Signaling

3 August 2017

published in

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3 August 2017

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3 August 2017

page(s)

e009

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Potential roles of ROR-alpha in cardiovascular endocrinology

3 August 2017

cites work

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7 July 2018

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7 July 2018

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7 July 2018

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Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells

7 July 2018

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Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

7 July 2018

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All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

7 July 2018

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The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation

7 July 2018

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X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

7 July 2018

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Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription

7 July 2018

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Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

7 July 2018

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The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

7 July 2018

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Identification of Reverb(alpha) as a novel ROR(alpha) target gene

7 July 2018

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Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter

7 July 2018

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Suppression of body fat accumulation in myostatin-deficient mice

7 July 2018

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The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

7 July 2018

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The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates

7 July 2018

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A serum shock induces circadian gene expression in mammalian tissue culture cells

7 July 2018

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Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis

7 July 2018

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A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

7 July 2018

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Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family

7 July 2018

1 reference

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Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation

7 July 2018

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A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb

7 July 2018

1 reference

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Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

7 July 2018

1 reference

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Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Chronic treatment with prednisolone represses the circadian oscillation of clock gene expression in mouse peripheral tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

A Nuclear Receptor Atlas: macrophage activation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Morning rise in blood pressure is a predictor of left ventricular hypertrophy in treated hypertensive patients

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Relevance of blood pressure variation in the circadian onset of cardiovascular events.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Aberrant expression of myosin isoforms in skeletal muscles from mice lacking the rev-erbAalpha orphan receptor gene

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Interleukin-6-deficient mice develop mature-onset obesity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Physical and inflammatory stressors elevate circadian clock gene mPer1 mRNA levels in the paraventricular nucleus of the mouse

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

An inherited functional circadian clock in zebrafish embryos.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472670

Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver

26 October 2018

1 reference

12 December 2020

Fibrates increase human REV-ERBalpha expression in liver via a novel peroxisome proliferator-activated receptor response element

1 reference

12 December 2020

Orphan nuclear hormone receptor RevErbalpha modulates expression from the promoter of the hydratase-dehydrogenase gene by inhibiting peroxisome proliferator-activated receptor alpha-dependent transactivation

1 reference

12 December 2020

Structure-function analysis of the Rev-erbA and RVR ligand-binding domains reveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains

1 reference

12 December 2020

Identifiers

DOI

10.1621/NRS.04009

1 reference

3 August 2017

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3 August 2017

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