Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase (Q34648600)

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English	Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

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James L Thomas

1

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3 August 2017

William L Duax

2

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Europe PubMed Central

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3 August 2017

Anthony Addlagatta

3

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3 August 2017

Stacey Brandt

4

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3 August 2017

Robert R Fuller

5

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3 August 2017

Wendy Norris

6

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3 August 2017

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publication date

27 June 2003

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3 August 2017

Journal of Biological Chemistry

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3 August 2017

278

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3 August 2017

37

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Europe PubMed Central

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3 August 2017

35483-35490

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PubMed publication ID

3 August 2017

Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase: purification from mitochondria and kinetic profiles, biophysical characterization of the purified mitochondrial and microsomal enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Dissecting human adrenal androgen production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase: purification from microsomes, substrate kinetics, and inhibition by product steroids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

An NADH-induced Conformational Change That Mediates the Sequential 3β-Hydroxysteroid Dehydrogenase/Isomerase Activities Is Supported by Affinity Labeling and the Time-dependent Activation of Isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Catalytic mechanism of an active-site mutant (D38N) of delta 5-3-ketosteroid isomerase. Direct spectroscopic evidence for dienol intermediates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Completeness in structural genomics.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Protein distance constraints predicted by neural networks and probability density functions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Functional activity of 3beta-hydroxysteroid dehydrogenase/isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

The engineered, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase: purification, characterization and crystallization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Critical Residues for the Specificity of Cofactors and Substrates in Human Estrogenic 17 -Hydroxysteroid Dehydrogenase 1: Variants Designed from the Three-Dimensional Structure of the Enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Affinity Radiolabeling Identifies Peptides Associated with the Isomerase Activity of Human Type I (Placental) 3β-Hydroxysteroid Dehydrogenase/Isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304752200

21 January 2018

Identifiers

10.1074/JBC.M304752200

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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