Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin. (Q34631045)

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7 February 2020

title

Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin (English)

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7 February 2020

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7 February 2020

Erik C Böttger

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7 February 2020

Rashid Akbergenov

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7 February 2020

Dmitri Shcherbakov

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7 February 2020

Tanja Matt

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7 February 2020

Stefan Duscha

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7 February 2020

Martin Meyer

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7 February 2020

language of work or name

English

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publication date

18 July 2011

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Antimicrobial Agents and Chemotherapy

7 February 2020

published in

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7 February 2020

volume

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7 February 2020

issue

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7 February 2020

page(s)

4712-4717

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The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome

7 February 2020

cites work

1 reference

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High level of cross-resistance between kanamycin, amikacin, and capreomycin among Mycobacterium tuberculosis isolates from Georgia and a close relation with mutations in the rrs gene

7 July 2018

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Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment.

7 July 2018

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Quantitative drug susceptibility testing of Mycobacterium tuberculosis by use of MGIT 960 and EpiCenter instrumentation

7 July 2018

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Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity

7 July 2018

1 reference

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Mutations in conserved helix 69 of 23S rRNA of Thermus thermophilus that affect capreomycin resistance but not posttranscriptional modifications

7 July 2018

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Mitochondrial deafness alleles confer misreading of the genetic code

7 July 2018

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Tuberculosis: drug resistance, fitness, and strategies for global control

7 July 2018

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Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria

7 July 2018

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Antimicrobial agents targeting the ribosome: the issue of selectivity and toxicity - lessons to be learned

7 July 2018

1 reference

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Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs

7 July 2018

1 reference

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Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

7 July 2018

1 reference

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Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis

7 July 2018

1 reference

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Maternally inherited aminoglycoside-induced and nonsyndromic deafness is associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family

7 July 2018

1 reference

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American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America

7 July 2018

1 reference

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Fitness cost of chromosomal drug resistance-conferring mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Structural basis for selectivity and toxicity of ribosomal antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

RecA-Mediated gene conversion and aminoglycoside resistance in strains heterozygous for rRNA.

7 July 2018

1 reference

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Community based approaches to the control of multidrug resistant tuberculosis: introducing "DOTS-plus".

7 July 2018

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In vitro and in vivo laboratory studies on the antituberculous activity of capreomycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Cross-resistance relationships between capreomycin, kanamycin, and viomycin resistances in tubecle bacilli from paients.

7 July 2018

1 reference

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Chloramphenicol toxicity: 25 years of research.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Viomycin resistance: Alterations of either ribosomal subunit affect the binding of the antibiotic to the pair subunit and the entire ribosome becomes resistant to the drug

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Resistance to viomycin conferred by RNA of either ribosomal subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

The Inhibition of Ribosomal Translocation by Viomycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187005

Cross-resistance in M. tuberculosis to kanamycin, capreomycin and viomycin

7 July 2018

1 reference

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Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

7 July 2018

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Conservation of bacterial protein synthesis machinery: initiation and elongation in Mycobacterium smegmatis

26 October 2018

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The antibiotic viomycin traps the ribosome in an intermediate state of translocation

26 October 2018

1 reference

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Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough

26 October 2018

1 reference

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Mutagenesis of 16S rRNA C1409-G1491 base-pair differentiates between 6'OH and 6'NH3+ aminoglycosides

26 October 2018

1 reference

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Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation

26 October 2018

1 reference

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Fitness of antibiotic-resistant microorganisms and compensatory mutations

26 October 2018

1 reference

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Mitochondrial ribosomal RNA mutation associated with both antibiotic–induced and non–syndromic deafness

26 October 2018

1 reference

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Worldwide Incidence of Multidrug‐Resistant Tuberculosis

26 October 2018

1 reference

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Misreading of RNA codewords induced by aminoglycoside antibiotics

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21768509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of translational errors (misreading) by tuberactinomycins and capreomycins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21768509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00628-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768509%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768509%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

21768509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21768509%20AND%20SRC:MED&resulttype=core&format=json