Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo (Q34634316)

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English	Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo	scientific article

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21 February 2020

Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo (English)

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21 February 2020

hepatocellular carcinoma

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21 February 2020

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21 February 2020

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Andreas Bender

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21 February 2020

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Chakrabhavi Dhananjaya Mohan

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21 February 2020

Hanumantharayappa Bharathkumar

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21 February 2020

Krishna C Bulusu

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21 February 2020

Vijay Pandey

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21 February 2020

Shobith Rangappa

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21 February 2020

Julian E Fuchs

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21 February 2020

Muthu K Shanmugam

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21 February 2020

Xiaoyun Dai

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21 February 2020

Feng Li

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21 February 2020

Amudha Deivasigamani

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21 February 2020

Alan Prem Kumar

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21 February 2020

Peter E Lobie

13

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21 February 2020

Basappa

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21 February 2020

Kanchugarakoppal S Rangappa

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21 February 2020

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15 October 2014

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21 February 2020

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12

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Journal of Biological Chemistry

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21 February 2020

289

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21 February 2020

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21 February 2020

34296-34307

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21 February 2020

Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines

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Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application

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Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

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7 July 2018

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Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells

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Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK

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γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro‐apoptotic and chemosensitizing agent

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Future perspectives in hepatocellular carcinoma

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Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway

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Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications

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Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma

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Cytosolic phospholipase A2 is an effector of Jak/STAT signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells

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Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo

1 reference

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A new small-molecule Stat3 inhibitor

1 reference

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12 December 2020

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Simplified staurosporine analogs as potent JAK3 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25320076

12 December 2020

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10.1074/JBC.M114.601104

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21 February 2020

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21 February 2020

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21 February 2020

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