Vitamin B12: unique metalorganic compounds and the most complex vitamins. (Q34621857)

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English	Vitamin B12: unique metalorganic compounds and the most complex vitamins.	scientific article

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

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title

Vitamin B12: unique metalorganic compounds and the most complex vitamins (English)

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

main subject

vitamin B12

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vitamin

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vitamin B

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author

Silvano Geremia

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2

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

Nicola Demitri

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3

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PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

Lucio Randaccio

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Lucio Randaccio

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

Jochen Wuerges

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4

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Jochen Wuerges

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

language of work or name

English

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publication date

30 April 2010

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

published in

Molecules

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

volume

15

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

issue

5

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

page(s)

3228-3259

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Europe PubMed Central

PMC publication ID

6257451

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

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8 February 2020

copyright license

Creative Commons Attribution 4.0 International

start time

30 April 2010

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April 2022 Public Data File from Crossref

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copyrighted

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cites work

Radical catalysis of B12 enzymes: structure, mechanism, inactivation, and reactivation of diol and glycerol dehydratases

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain alternation switches B(12)-dependent methionine synthase to the activation conformation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Comparative analysis of cobalamin binding kinetics and ligand protection for intrinsic factor, transcobalamin, and haptocorrin.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-induced transmembrane signaling in the cobalamin transporter BtuB

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radical carbon skeleton rearrangements: catalysis by coenzyme B12-dependent mutases

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radical catalysis in coenzyme B12-dependent isomerization (eliminating) reactions

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequencing of glutamate mutase component S from Clostridium tetanomorphum. Homologies with other cobalamin-dependent enzymes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Composite organization of the cobalamin binding and cubilin recognition sites of intrinsic factor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemistry and enzymology of vitamin B12.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectroscopic and computational studies of the ATP:corrinoid adenosyltransferase (CobA) from Salmonella enterica: insights into the mechanism of adenosylcobalamin biosynthesis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilisation of methylene radicals by cob(II)alamin in coenzyme B12 dependent mutases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin B12: a methyl group without a job?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for mammalian vitamin B12 transport by transcobalamin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

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inferred from PubMed ID database lookup

Outer membrane active transport: structure of the BtuB:TonB complex

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural insights into methyltransfer reactions of a corrinoid iron-sulfur protein involved in acetyl-CoA synthesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characterization of the active site of the PduO-type ATP:Co(I)rrinoid adenosyltransferase from Lactobacillus reuteri.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B12 trafficking in mammals: A for coenzyme escort service

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does Cob(II)alamin act as a conductor in coenzyme B12 dependent mutases?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of ATP-bound human ATP:cobalamin adenosyltransferase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural study on ligand specificity of human vitamin B12 transporters

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of discrimination between cobalamins and their natural analogues during their binding to the specific B12-transporting proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitroxylcob(III)alamin: synthesis and X-ray structural characterization

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand trans influence governs conformation in cobalamin-dependent methionine synthase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin B12 transport proteins: crystallographic analysis of beta-axial ligand substitutions in cobalamin bound to transcobalamin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal active site elasticity linked to activation of homocysteine in methionine synthases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New derivatives of vitamin B12 show preferential targeting of tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characterization of a human-type corrinoid adenosyltransferase confirms that coenzyme B12 is synthesized through a four-coordinate intermediate

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin B12-mediated transport: a potential tool for tumor targeting of antineoplastic drugs and imaging agents

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Traveling the vitamin B12 pathway: oral delivery of protein and peptide drugs

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring the implications of vitamin B12 conjugation to insulin on insulin receptor binding

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR spectroscopy and molecular modelling studies of nitrosylcobalamin: further evidence that the deprotonated, base-off form is important for nitrosylcobalamin in solution.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Residue Phe112 of the Human-Type Corrinoid Adenosyltransferase (PduO) Enzyme of Lactobacillus reuteri Is Critical to the Formation of the Four-Coordinate Co(II) Corrinoid Substrate and to the Activity of the Enzyme † , ‡

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tyrosine residue in the activation of Co-C bond in coenzyme B12-dependent enzymes: another case of proton-coupled electron transfer?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High resolution crystal structure of the methylcobalamin analogues ethylcobalamin and butylcobalamin by X-ray synchrotron diffraction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of toxic Gd3+ ions to tumour cells by vitamin B12 bioconjugates.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the cubilin receptor through the vitamin B(12) uptake pathway: cytotoxicity and mechanistic insight through fluorescent Re(I) delivery.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tinker, tailor, soldier in intracellular B12 trafficking

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axial bonding in alkylcobalamins: DFT analysis of the inverse versus normal trans influence

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organometallic chemistry of b(12) coenzymes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cobalamin- and corrinoid-dependent enzymes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coenzyme B 12 as common hydrogen transferrer of dioldehydrase-and methylmalonyl-Co A -mutase reaction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the Mechanism of Hydrogen Transfer in the Cobamide Coenzyme-dependent Dioldehydrase Reaction

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20657474

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3390/MOLECULES15053228

1 reference

stated in

Europe PubMed Central

PMC publication ID

6257451

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

retrieved

8 February 2020

PMC publication ID

6257451

1 reference

stated in

Europe PubMed Central

PMC publication ID

6257451

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

retrieved

8 February 2020

PubMed publication ID

20657474

1 reference

stated in

Europe PubMed Central

PMC publication ID

6257451

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20657474%20AND%20SRC:MED&resulttype=core&format=json

retrieved

8 February 2020

ResearchGate publication ID

45288375

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