The structural determinants of checkpoint activation (Q34619662)

3 August 2017

title

The structural determinants of checkpoint activation (English)

1 reference

3 August 2017

author name string

Christina A MacDougall

1 reference

3 August 2017

Tony S Byun

1 reference

3 August 2017

Christopher Van

1 reference

3 August 2017

Muh-ching Yee

1 reference

3 August 2017

Karlene A Cimprich

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3 August 2017

publication date

1 April 2007

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

898-903

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The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint

3 August 2017

cites work

1 reference

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DNA nucleotide excision repair-dependent signaling to checkpoint activation

7 July 2018

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Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions

7 July 2018

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TopBP1 activates the ATR-ATRIP complex

7 July 2018

1 reference

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Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus

7 July 2018

1 reference

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Right place, right time, and only once: replication initiation in metazoans

7 July 2018

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Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response

7 July 2018

1 reference

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Preventing re-replication of chromosomal DNA.

7 July 2018

1 reference

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Identification and functional analysis of TopBP1 and its homologs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

7 July 2018

1 reference

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

7 July 2018

1 reference

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A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

7 July 2018

1 reference

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7 July 2018

The Chk2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex

7 July 2018

1 reference

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Regulation of DNA replication by ATR: signaling in response to DNA intermediates

7 July 2018

1 reference

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ATR and ATM regulate the timing of DNA replication origin firing

7 July 2018

1 reference

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UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Replication protein A-mediated recruitment and activation of Rad17 complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

A unified view of the DNA-damage checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

The DNA damage response: putting checkpoints in perspective

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Activation of the DNA replication checkpoint through RNA synthesis by primase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Regulated chromosomal DNA replication in the absence of a nucleus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Geminin, an inhibitor of DNA replication, is degraded during mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

DNA replication in vitro by recombinant DNA-polymerase-alpha-primase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

DNA synthesis in a cell-free system from Xenopus eggs: Priming and elongation on single-stranded DNA in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

A central role for DNA replication forks in checkpoint activation and response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847708

Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17437996

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1522607

1 reference

release_crafc73nevgvjgykrsddpqad5i

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/crafc73nevgvjgykrsddpqad5i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

1847708

1 reference

3 August 2017

1 reference