Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway (Q34606483)

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English	Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

cystic fibrosis

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toll-like receptor

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molecular biology

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Sanjay H. Chotirmall

object named as

Sanjay H Chotirmall

2

0 references

Catherine M Greene

object named as

Catherine M Greene

3

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author name string

Sonya Cosgrove

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Noel G McElvaney

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

30 December 2010

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

number of pages

13

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

286

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

7692-7704

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Neutrophil elastase increases airway epithelial nonheme iron levels

1 reference

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Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.

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7 July 2018

miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression

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THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN.

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Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery

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7 July 2018

Role of the cysteine protease interpain A of Prevotella intermedia in breakdown and release of haem from haemoglobin

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7 July 2018

Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases.

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7 July 2018

Hemoglobin research and the origins of molecular medicine.

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7 July 2018

Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis

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7 July 2018

Meprins, membrane-bound and secreted astacin metalloproteinases

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Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.

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A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation

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7 July 2018

Heme as a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis

1 reference

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7 July 2018

Heme is involved in microRNA processing

1 reference

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7 July 2018

Heme regulates allosteric activation of the Slo1 BK channel

1 reference

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7 July 2018

Cooperativity and pseudo-cooperativity in the glutathione S-transferase from Plasmodium falciparum.

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7 July 2018

Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells.

1 reference

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7 July 2018

Elastolytic proteases: inflammation resolution and dysregulation in chronic infective lung disease.

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7 July 2018

Degradation of pulmonary surfactant protein D by Pseudomonas aeruginosa elastase abrogates innate immune function

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7 July 2018

Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

1 reference

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7 July 2018

Expression of meprins in health and disease

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7 July 2018

Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability

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7 July 2018

Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045023

7 July 2018

Inhibition of neutrophil elastase in CF sputum by L-658,758.

1 reference

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7 July 2018

Hemoglobin as a source of endogenous bioactive peptides: The concept of tissue-specific peptide pool

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7 July 2018

Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage

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7 July 2018

Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.

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An Immortalized Cystic Fibrosis Tracheal Epithelial Cell Line Homozygous for the ΔF508 CFTR Mutation

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7 July 2018

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line

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Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte

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7 July 2018

Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression.

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21 January 2018

Characterization of heme as activator of Toll-like receptor 4.

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21 January 2018

Protoporphyrin IX-induced structural and functional changes in human red blood cells, haemoglobin and myoglobin

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An improved colorimetric method for quantitation of heme using tetramethylbenzidine as substrate

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21 January 2018

17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor

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Aerosol α1 -antitrypsin treatment for cystic fibrosis

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12 December 2020

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Alpha-1 antitrypsin deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/21193404

12 December 2020

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Neokyotorphin and neokyotorphin (1-4): secretion by erythrocytes and regulation of tumor cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21193404

12 December 2020

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Heme Induces Neutrophil Migration and Reactive Oxygen Species Generation through Signaling Pathways Characteristic of Chemotactic Receptors

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.M110.183863

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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