MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway. (Q34606028)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

CCAAT/enhancer binding protein (C/EBP), alpha

1 reference

GOA release 2020-03-11

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Tatyana Veremeyko

1 reference

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17 January 2020

Anna M Krichevsky

series ordinal

1 reference

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17 January 2020

Howard L Weiner

series ordinal

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

5 December 2010

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17 January 2020

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17 January 2020

volume

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17 January 2020

issue

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17 January 2020

page(s)

64-70

1 reference

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CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter

17 January 2020

cites work

1 reference

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miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

7 July 2018

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miR-21: a small multi-faceted RNA.

7 July 2018

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MicroRNAs: key regulators of stem cells

7 July 2018

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Viral and cellular messenger RNA targets of viral microRNAs

7 July 2018

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

7 July 2018

1 reference

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MicroRNAs: novel regulators during the immune response.

7 July 2018

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miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells

7 July 2018

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MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

7 July 2018

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Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma

7 July 2018

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

7 July 2018

1 reference

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Bone-marrow-derived microglia: myth or reality?

7 July 2018

1 reference

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PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells

7 July 2018

1 reference

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miRiad roles for the miR-17-92 cluster in development and disease

7 July 2018

1 reference

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A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis

7 July 2018

1 reference

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Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

7 July 2018

1 reference

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C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

7 July 2018

1 reference

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The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

A mammalian microRNA expression atlas based on small RNA library sequencing

7 July 2018

1 reference

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An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

RT-PCR-based analysis of microRNA (miR-1 and -124) expression in mouse CNS

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Regulation of miRNA expression during neural cell specification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

The functions of animal microRNAs

7 July 2018

1 reference

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Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

7 July 2018

1 reference

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PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

The transcription factor PU.1 is involved in macrophage proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

The 55-kD tumor necrosis factor receptor on human keratinocytes is regulated by tumor necrosis factor-alpha and by ultraviolet B radiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Functional analysis of PU.1 domains in monocyte-specific gene regulation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

CCAAT-enhancer binding protein alpha is expressed in activated microglial cells after brain injury.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044940

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

26 October 2018

1 reference

12 December 2020

Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes

1 reference

12 December 2020

Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

MicroRNAs loom large in the heart

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21131957

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131957%20AND%20SRC:MED&resulttype=core&format=json