Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity (Q34594124)

3 August 2017

title

Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity (English)

1 reference

3 August 2017

García-Herrero CM

1 reference

3 August 2017

Galán M

1 reference

3 August 2017

Vincent O

1 reference

3 August 2017

Flández B

1 reference

3 August 2017

Gargallo M

1 reference

3 August 2017

Delgado-Alvarez E

1 reference

3 August 2017

Blázquez E

1 reference

3 August 2017

Navas MA

1 reference

3 August 2017

language of work or name

1 reference

21 December 2006

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

3 August 2017

page(s)

325-333

1 reference

Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2).

3 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0542-7

Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0542-7

A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate

21 January 2018

1 reference

12 December 2020

Short-term control of glucokinase activity: role of a regulatory protein

1 reference

12 December 2020

Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.

1 reference

12 December 2020

The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis

1 reference

12 December 2020

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

1 reference

12 December 2020

Overexpression of fructose 2,6-bisphosphatase decreases glycolysis and delays cell cycle progression

1 reference

12 December 2020

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

1 reference

12 December 2020

Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability

1 reference

12 December 2020

Permanent neonatal diabetes in an Asian infant.

1 reference

12 December 2020

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young

1 reference

12 December 2020

A simple salting out procedure for extracting DNA from human nucleated cells

1 reference

12 December 2020

Regulation of β cell glucokinase by S-nitrosylation and association with nitric oxide synthase

1 reference

12 December 2020

Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes

1 reference

12 December 2020

beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations

1 reference

12 December 2020

Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein

1 reference

12 December 2020

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

1 reference

12 December 2020

Glucokinase, glucose homeostasis, and diabetes mellitus

1 reference

12 December 2020

A novel glucokinase regulator in pancreatic beta cells: precursor of propionyl-CoA carboxylase beta subunit interacts with glucokinase and augments its activity

1 reference

12 December 2020

Glucokinase and glucose homeostasis: proven concepts and new ideas

1 reference

12 December 2020

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

1 reference

12 December 2020

Effect of mutations on the sensitivity of human beta-cell glucokinase to liver regulatory protein

1 reference

12 December 2020

Interaction of glucokinase with the liver regulatory protein is conferred by leucine-asparagine motifs of the enzyme

1 reference

12 December 2020

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

1 reference

12 December 2020

MODY 2 presenting as neonatal hyperglycaemia: a need to reshape the definition of "neonatal diabetes"?

1 reference

12 December 2020

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

1 reference

12 December 2020

RASMOL: biomolecular graphics for all

1 reference

12 December 2020

Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain

1 reference

12 December 2020

Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells

1 reference

12 December 2020

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships

1 reference

12 December 2020

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase

1 reference

12 December 2020

Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus

1 reference

12 December 2020

10.1007/S00125-006-0542-7

Identifiers

DOI

1 reference

Dimensions Publication ID

3 August 2017

1032120121

0 references

1 reference