Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis (Q34581804)

3 August 2017

title

Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis (English)

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3 August 2017

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Alfred Ayala

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3 August 2017

Lyle L Moldawer

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3 August 2017

Philip O Scumpia

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3 August 2017

Matthew J Delano

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3 August 2017

Kindra M Kelly-Scumpia

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3 August 2017

Jason S Weinstein

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3 August 2017

James L Wynn

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3 August 2017

Robert D Winfield

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3 August 2017

Changqing Xia

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3 August 2017

Chun Shiang Chung

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3 August 2017

Mark A Atkinson

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3 August 2017

Westley H Reeves

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3 August 2017

Michael J Clare-Salzler

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3 August 2017

language of work or name

English

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publication date

9 August 2007

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3 August 2017

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3 August 2017

volume

110

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3 August 2017

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3 August 2017

page(s)

3673-3681

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The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis

3 August 2017

cites work

1 reference

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Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.

7 July 2018

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The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

7 July 2018

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In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

7 July 2018

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Adoptive transfer of in vitro-stimulated CD4+CD25+ regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis

7 July 2018

1 reference

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GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily

7 July 2018

1 reference

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TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response

7 July 2018

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Toll-like receptor ligands directly promote activated CD4+ T cell survival

7 July 2018

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GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

7 July 2018

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7 July 2018

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

7 July 2018

1 reference

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Prolonged exposure of T cells to TNF down-regulates TCR zeta and expression of the TCR/CD3 complex at the cell surface.

7 July 2018

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L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells.

7 July 2018

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Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

7 July 2018

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Prevention of lymphocyte cell death in sepsis improves survival in mice

7 July 2018

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Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis

7 July 2018

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Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses

7 July 2018

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Host Resistance in Sepsis and Trauma

7 July 2018

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IL-1 beta breaks tolerance through expansion of CD25+ effector T cells.

7 July 2018

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CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress

27 October 2018

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Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

27 October 2018

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Cutting edge: ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis

27 October 2018

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Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

27 October 2018

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Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

27 October 2018

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12 December 2020

Cutting edge: TLR2 directly triggers Th1 effector functions

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12 December 2020

Monocyte deactivation in septic patients: restoration by IFN-gamma treatment

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12 December 2020

Major Injury Induces Increased Production of Interleukin-10 by Cells of the Immune System With a Negative Impact on Resistance to Infection

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12 December 2020

Selective defects of T lymphocyte function in patients with lethal intraabdominal infection

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12 December 2020

Protective effects of early interleukin 10 antagonism on injury-induced immune dysfunction

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12 December 2020

The role of TCR engagement and activation-induced cell death in sepsis-induced T cell apoptosis

1 reference

12 December 2020

10.1182/BLOOD-2007-04-087171

Identifiers

DOI

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3 August 2017

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3 August 2017

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