Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung (Q34573221)

3 August 2017

title

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung (English)

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3 August 2017

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Tim Willinger

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Hitoshi Takizawa

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Markus G Manz

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Andrew J Murphy

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Richard A Flavell

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3 August 2017

Anthony Rongvaux

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3 August 2017

Elizabeth E Eynon

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3 August 2017

Wojtek Auerbach

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3 August 2017

David Salazar-Valenzuela

series ordinal

object named as

David M Valenzuela

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3 August 2017

Sean Stevens

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3 August 2017

George D Yancopoulos

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3 August 2017

language of work or name

English

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publication date

24 January 2011

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

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inferred from page(s)

published in

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3 August 2017

volume

108

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3 August 2017

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3 August 2017

page(s)

2390-2395

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Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations

3 August 2017

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7 July 2018

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The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells

7 July 2018

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IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense

7 July 2018

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7 July 2018

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Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity

7 July 2018

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The pulmonary alveolar proteinosis in granulocyte macrophage colony-stimulating factor/interleukins 3/5 beta c receptor-deficient mice is reversed by bone marrow transplantation

7 July 2018

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Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

7 July 2018

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Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

7 July 2018

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7 July 2018

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Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

21 January 2018

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Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

21 January 2018

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The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

21 January 2018

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Protective effects of recombinant human granulocyte macrophage colony stimulating factor on H1N1 influenza virus-induced pneumonia in mice.

21 January 2018

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Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

21 January 2018

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GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.

27 October 2018

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Human-Hemato-Lymphoid-System Mice: Opportunities and Challenges

27 October 2018

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IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R c-/- Mice without Affecting Peripheral T Cell Homeostasis

27 October 2018

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Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

21 January 2018

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12 December 2020

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

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12 December 2020

NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration

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12 December 2020

Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions

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12 December 2020

Involvement of interleukin-3 in delayed-type hypersensitivity

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1019682108

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3 August 2017

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3 August 2017

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