PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice (Q34577678)

3 August 2017

title

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice (English)

1 reference

3 August 2017

Tasuku Honjo

1 reference

3 August 2017

Fumio Nakaki

0 references

Daisuke Sugiura

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Il-mi Okazaki

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Masamichi Muramatsu

1 reference

3 August 2017

Sidonia Fagarasan

1 reference

3 August 2017

Taku Okazaki

1 reference

3 August 2017

Jian Wang

1 reference

3 August 2017

Taku Yoshida

1 reference

3 August 2017

Yu Kato

1 reference

3 August 2017

Tomoo Eto

1 reference

3 August 2017

Kyoji Hioki

1 reference

3 August 2017

language of work or name

English

0 references

publication date

7 February 2011

1 reference

Journal of Experimental Medicine

3 August 2017

published in

1 reference

3 August 2017

volume

208

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3 August 2017

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3 August 2017

page(s)

395-407

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On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection

3 August 2017

cites work

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Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

7 July 2018

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LAG-3 regulates plasmacytoid dendritic cell homeostasis

7 July 2018

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7 July 2018

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CTLA-4 control over Foxp3+ regulatory T cell function

7 July 2018

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Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease

7 July 2018

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PD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice

7 July 2018

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PD-1 and its ligands in tolerance and immunity

7 July 2018

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LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems

7 July 2018

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Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice

7 July 2018

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Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling

7 July 2018

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The PD-1-PD-L pathway in immunological tolerance

7 July 2018

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Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice

7 July 2018

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Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes

7 July 2018

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Role of LAG-3 in regulatory T cells.

7 July 2018

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Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo

7 July 2018

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Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

7 July 2018

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7 July 2018

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

7 July 2018

1 reference

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

7 July 2018

1 reference

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Control of regulatory T cell development by the transcription factor Foxp3

7 July 2018

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Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3

7 July 2018

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Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3).

7 July 2018

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The AID enzyme induces class switch recombination in fibroblasts

7 July 2018

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Molecular mechanism of class switch recombination: linkage with somatic hypermutation

7 July 2018

1 reference

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Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

7 July 2018

1 reference

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CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling.

7 July 2018

1 reference

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Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome

7 July 2018

1 reference

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Characterization of the major histocompatibility complex class II binding site on LAG-3 protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

7 July 2018

1 reference

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Independent modes of natural killing distinguished in mice lacking Lag3

7 July 2018

1 reference

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A novel ES cell line, TT2, with high germline-differentiating potency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

LAG-3, a novel lymphocyte activation gene closely related to CD4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity in lpr mice on a C57BL/6 background

7 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100466

Macrophage C-type lectin on bone marrow-derived immature dendritic cells is involved in the internalization of glycosylated antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100466

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100466

Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100466

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100466

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039848

Investigation of the role of B-cells in type 1 diabetes in the NOD mouse

27 October 2018

1 reference

12 December 2020

Development of Insulitis and Diabetes in B Cell-Deficient NOD Mice

1 reference

12 December 2020

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

1 reference

12 December 2020

Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223)

1 reference

12 December 2020

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20100466

1 reference

3 August 2017

1 reference

3 August 2017

1 reference