Withania somnifera water extract as a potential candidate for differentiation based therapy of human neuroblastomas (Q34576380)

3 August 2017

title

Withania somnifera water extract as a potential candidate for differentiation based therapy of human neuroblastomas (English)

1 reference

3 August 2017

Withania somnifera

1 reference

Hardeep Kataria

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Renu Wadhwa

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Sunil C Kaul

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Gurcharan Kaur

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3 August 2017

language of work or name

English

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publication date

31 January 2013

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

e55316

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Creative Commons Attribution 4.0 International

3 August 2017

start time

31 January 2013

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Water extract from the leaves of Withania somnifera protect RA differentiated C6 and IMR-32 cells against glutamate-induced excitotoxicity

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Mortalin overexpression attenuates beta-amyloid-induced neurotoxicity in SH-SY5Y cells.

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In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and β‐amyloid(1–42)‐induced cytotoxicity in differentiated PC12 cells

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Water extract of ashwagandha leaves limits proliferation and migration, and induces differentiation in glioma cells

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7 July 2018

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Withanolide sulfoxide from Aswagandha roots inhibits nuclear transcription factor-kappa-B, cyclooxygenase and tumor cell proliferation

7 July 2018

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Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis

7 July 2018

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Selective killing of cancer cells by leaf extract of Ashwagandha: components, activity and pathway analyses

7 July 2018

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CMP substitutions preferentially inhibit polysialic acid synthesis

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Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo.

7 July 2018

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BM88 is a dual function molecule inducing cell cycle exit and neuronal differentiation of neuroblastoma cells via cyclin D1 down-regulation and retinoblastoma protein hypophosphorylation

7 July 2018

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Novel functions for cell cycle genes in nervous system development

7 July 2018

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7 July 2018

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7 July 2018

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Cytoplasmic sequestration of cyclin D1 associated with cell cycle withdrawal of neuroblastoma cells

7 July 2018

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Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR.

7 July 2018

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Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells

7 July 2018

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Neuritic regeneration and synaptic reconstruction induced by withanolide A

7 July 2018

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Celastrols as inducers of the heat shock response and cytoprotection.

7 July 2018

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Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

7 July 2018

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Trk receptors: roles in neuronal signal transduction

7 July 2018

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7 July 2018

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Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation.

7 July 2018

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Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha.

7 July 2018

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Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

7 July 2018

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7 July 2018

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7 July 2018

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The distribution of heat shock proteins in the nervous system of the unstressed mouse embryo suggests a role in neuronal and non-neuronal differentiation

7 July 2018

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Regulation of neural cell adhesion molecule polysialylation state by cell-cell contact and protein kinase C delta

7 July 2018

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The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation

7 July 2018

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Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

7 July 2018

1 reference

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Requirement of heavy neurofilament subunit in the development of axons with large calibers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Cyclin D1 and human neoplasia

7 July 2018

1 reference

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Regulation of Neural Cell Adhesion Molecule Polysialylation: Evidence for Nontranscriptional Control and Sensitivity to an Intracellular Pool of Calcium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Polysialic acid on the neural cell adhesion molecule correlates with expression of polysialyltransferases and promotes neuroblastoma cell growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Cell biology of polysialic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Differential Expression of NeuroD in Primary Cultures of Cerebral Cortical Neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Changing views of the role of matrix metalloproteinases in metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Genomic structure and promoter activity of the mouse polysialic acid synthase gene (mST8Sia II). Brain-specific expression from a TATA-less GC-rich sequence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Possible roles of tumor-associated carbohydrate antigens.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Heat shock gene expression and development. II. An overview of mammalian and avian developmental systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Integrins and cell adhesion molecules: neuronal receptors that regulate axon growth on extracellular matrices and cell surfaces

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Stable clathrin: uncoating protein (hsc70) complexes in intact neurons and their axonal transport

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Over-expression of cyclin D1 induces glioma invasion by increasing matrix metalloproteinase activity and cell motility.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Phase II study on the effect of disease sites, age, and prior therapy on response to iodine-131-metaiodobenzylguanidine therapy in refractory neuroblastoma.

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Structures of withanosides I, II, III, IV, V, VI, and VII, new withanolide glycosides, from the roots of Indian Withania somnifera DUNAL. and inhibitory activity for tachyphylaxis to clonidine in isolated guinea-pig ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Withanolides from Withania somnifera roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Neural differentiation and the attenuated heat shock response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Effect of the alcoholic extract of Ashwagandha leaves and its components on proliferation, migration, and differentiation of glioblastoma cells: combinational approach for enhanced differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Genomic Structure and Promoter Activity of the Mouse Polysialic Acid Synthase (mST8Sia IV/PST) Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Role of cellular energy status in tocopheryl hemisuccinate cytoprotection against ethyl methanesulfonate-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Withanamides in Withania somnifera fruit protect PC-12 cells from beta-amyloid responsible for Alzheimer's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Protective effect of Withania somnifera dunal root extract against protracted social isolation induced behavior in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Localization of phosphorylated cAMP response element-binding protein in immature neurons of adult hippocampus.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561198

Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells

27 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055316

Neuroblastoma incidence and survival in European children (1978–1997): Report from the Automated Childhood Cancer Information System project

21 January 2018

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12 December 2020

Polysialic acid: three-dimensional structure, biosynthesis and function

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12 December 2020

1,4-Dioxane and ergosterol derivatives fromWithania somniferaroots

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12 December 2020

Cyclin D1 expression in astrocytomas is associated with cell proliferation activity and patient prognosis

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12 December 2020

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

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12 December 2020

Restricted localization of L1 and N-CAM at sites of contact between Schwann cells and neurites in culture

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12 December 2020

N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells

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12 December 2020

Mortalin inhibition in experimental Parkinson's disease

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0055316

Identifiers

DOI

1 reference

release_nktd4pucvbdopoqo64jrv7unxq

3 August 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nktd4pucvbdopoqo64jrv7unxq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3561198

1 reference

3 August 2017

1 reference