Ontogeny of dextromethorphan O- and N-demethylation in the first year of life (Q34575597)

3 August 2017

title

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life (English)

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3 August 2017

James LP

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3 August 2017

Kearns GL

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3 August 2017

Blake MJ

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3 August 2017

Gaedigk A

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3 August 2017

Pearce RE

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3 August 2017

Bomgaars LR

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3 August 2017

Christensen ML

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3 August 2017

Stowe C

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3 August 2017

Wilson JT

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3 August 2017

Leeder JS

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3 August 2017

language of work or name

English

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publication date

14 February 2007

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Clinical Pharmacology & Therapeutics

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

510-516

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Off-label and unlicensed prescribing for newborns and children in different settings: a review of the literature and a consideration about drug safety

3 August 2017

cites work

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Discovery of a novel nonfunctional cytochrome P450 2D6 allele, CYP2D642, in African American subjects

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CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism

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Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans

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CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status

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CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans

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Cytochrome P450 3A: ontogeny and drug disposition

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7 January 2021

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

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Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation

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Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension

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Multiple dose pharmacokinetics of paroxetine in children and adolescents with major depressive disorder or obsessive-compulsive disorder

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Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

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7 January 2021

Investigation of terbinafine as a CYP2D6 inhibitor in vivo.

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7 January 2021

Omission of the deconjugation step in urine analysis and the unaltered outcome of CYP2D6 phenotyping with dextromethorphan

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7 January 2021

Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes

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7 January 2021

Potential Fluoxetine Chloride (Prozac) Toxicity in a Newborn

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7 January 2021

Neonatal paroxetine withdrawal syndrome

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7 January 2021

Identifiers

DOI

10.1038/SJ.CLPT.6100101

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Dimensions Publication ID

3 August 2017

1040229074

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