Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells (Q34574786)

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English	Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

7

object named as

Max S Wicha

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Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Ming Luo

1

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Europe PubMed Central

PubMed publication ID

3 August 2017

Huaping Fan

2

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Europe PubMed Central

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3 August 2017

Tamas Nagy

3

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Europe PubMed Central

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3 August 2017

Huijun Wei

4

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Europe PubMed Central

PubMed publication ID

3 August 2017

Chenran Wang

5

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Europe PubMed Central

PubMed publication ID

3 August 2017

Suling Liu

6

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Europe PubMed Central

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3 August 2017

Jun-Lin Guan

8

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Europe PubMed Central

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3 August 2017

language of work or name

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publication date

1 January 2009

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Europe PubMed Central

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3 August 2017

Cancer Research

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Europe PubMed Central

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3 August 2017

69

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Europe PubMed Central

PubMed publication ID

3 August 2017

2

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Europe PubMed Central

PubMed publication ID

3 August 2017

466-474

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Europe PubMed Central

PubMed publication ID

3 August 2017

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Identification of tumor-initiating cells in a p53-null mouse model of breast cancer

1 reference

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7 July 2018

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.

1 reference

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7 July 2018

Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

1 reference

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7 July 2018

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

1 reference

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7 July 2018

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

1 reference

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7 July 2018

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Focal adhesion kinase and p53 signaling in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Modelling breast cancer: one size does not fit all.

1 reference

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7 July 2018

The properties of a mammary gland cancer stem cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Crossing paths with Notch in the hyper-network

1 reference

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7 July 2018

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Mammary stem cells and mammopoiesis

1 reference

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7 July 2018

Cancer stem cells: models and concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Steroid hormone receptor status of mouse mammary stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.

1 reference

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7 July 2018

Cancer stem cells: an old idea--a paradigm shift

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Generation of a functional mammary gland from a single stem cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Purification and unique properties of mammary epithelial stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

1 reference

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7 July 2018

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Wnt signalling in stem cells and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Focal adhesion kinase: in command and control of cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Diverse mechanisms regulate stem cell self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

The Hedgehog response network: sensors, switches, and routers

1 reference

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7 July 2018

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

1 reference

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7 July 2018

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Focal adhesion kinase: the first ten years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Prospective identification of tumorigenic breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression

1 reference

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7 July 2018

Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology

1 reference

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7 July 2018

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

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7 July 2018

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

7 July 2018

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

27 October 2018

High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

27 October 2018

Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

27 October 2018

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039129

27 October 2018

Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An entire functional mammary gland may comprise the progeny from a single cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-3078

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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