Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments (Q34568577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25436017%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments (English)

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23 February 2020

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23 February 2020

Celine Denais

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23 February 2020

Maya C Bakshi

series ordinal

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23 February 2020

Jan Lammerding

series ordinal

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23 February 2020

publication date

1 September 2014

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Cellular and Molecular Bioengineering

23 February 2020

number of pages

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inferred from page(s)

published in

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23 February 2020

volume

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23 February 2020

issue

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23 February 2020

page(s)

293-306

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describes a project that uses

23 February 2020

ImageJ

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

cites work

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

1 reference

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7 July 2018

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Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

7 July 2018

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Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation

7 July 2018

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Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

7 July 2018

1 reference

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Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force

7 July 2018

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7 July 2018

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At the leading edge of three-dimensional cell migration

7 July 2018

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Hutchinson-Gilford progeria syndrome alters nuclear shape and reduces cell motility in three dimensional model substrates

7 July 2018

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7 July 2018

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The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration

7 July 2018

1 reference

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Physical confinement alters tumor cell adhesion and migration phenotypes.

7 July 2018

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7 July 2018

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Chemotaxis of cell populations through confined spaces at single-cell resolution

7 July 2018

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The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

7 July 2018

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Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer.

7 July 2018

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Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

7 July 2018

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Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Lamins A and C but not lamin B1 regulate nuclear mechanics.

21 January 2018

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A modified micropipette aspiration technique and its application to tether formation from human neutrophils

21 January 2018

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A close-up view of migrating Langerhans cells in the skin.

21 January 2018

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The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer.

21 January 2018

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Intravital third harmonic generation microscopy of collective melanoma cell invasion: Principles of interface guidance and microvesicle dynamics.

21 January 2018

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New dimensions in cell migration

21 January 2018

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10.1007/S12195-014-0342-Y

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

23 February 2020

0 references

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23 February 2020

PubMed publication ID

25436017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25436017%20AND%20SRC:MED&resulttype=core&format=json