The retinoblastoma protein regulates pericentric heterochromatin (Q34564813)

3 August 2017

title

The retinoblastoma protein regulates pericentric heterochromatin (English)

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3 August 2017

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Piotr Sicinski

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3 August 2017

Christian E Isaac

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3 August 2017

Sarah M Francis

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3 August 2017

Alison L Martens

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3 August 2017

Lisa M Julian

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3 August 2017

Laurie A Seifried

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3 August 2017

Natalie Erdmann

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3 August 2017

Ulrich K Binné

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3 August 2017

Lea Harrington

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3 August 2017

Nathalie G Bérubé

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3 August 2017

Nicholas J Dyson

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3 August 2017

Frederick A Dick

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3 August 2017

language of work or name

English

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publication date

1 May 2006

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Molecular and Cellular Biology

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

3659-3671

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Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging

3 August 2017

cites work

1 reference

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

7 July 2018

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How cells coordinate growth and division

7 July 2018

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Living with or without cyclins and cyclin-dependent kinases

7 July 2018

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Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

7 July 2018

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Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Chromatin dynamics at DNA replication, transcription and repair

7 July 2018

1 reference

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A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

7 July 2018

1 reference

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Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

7 July 2018

1 reference

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Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase

7 July 2018

1 reference

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A revised picture of the E2F transcriptional network and RB function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes

7 July 2018

1 reference

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The RB and p53 pathways in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Functional antagonism between E2F family members

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Translating the Histone Code

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Rb targets histone H3 methylation and HP1 to promoters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Retinoblastoma protein partners

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

The Rb/E2F pathway: expanding roles and emerging paradigms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

De novo nucleosome assembly: new pieces in an old puzzle

7 July 2018

1 reference

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Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

7 July 2018

1 reference

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7 July 2018

The Hallmarks of Cancer

1 reference

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Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

7 July 2018

1 reference

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Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

pRB plays an essential role in cell cycle arrest induced by DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

7 July 2018

1 reference

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The regulation of E2F by pRB-family proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Rb interacts with histone deacetylase to repress transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Retinoblastoma protein recruits histone deacetylase to repress transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

E2F Activity Is Regulated by Cell Cycle-Dependent Changes in Subcellular Localization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Gene targeting for somatic cell manipulation: rapid analysis of reduced chromosome hybrids by Alu-PCR fingerprinting and chromosome painting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

FACS-based detection of phosphorylated histone H3 for the quantitation of mitotic cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

Loss of Rb overrides the requirement for ERK activity for cell proliferation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447412

A role for the Rb family of proteins in controlling telomere length

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16612004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.26.9.3659-3671.2006

1 reference

release_xhnsvl4i45fkllhmsxvilef2re

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xhnsvl4i45fkllhmsxvilef2re

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

1447412

1 reference

3 August 2017

1 reference