A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase (Q34552596)

3 August 2017

title

A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase (English)

1 reference

3 August 2017

1 reference

Andras Boeszoermenyi

0 references

Christoph Heier

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Monika Oberer

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Martina Schweiger

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Achim Lass

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Robert Zimmermann

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Rudolf Zechner

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Ines K Cerk

1 reference

3 August 2017

Barbara Salzburger

1 reference

3 August 2017

Christoph Pillip

1 reference

3 August 2017

Matthias Romauch

1 reference

3 August 2017

Irina Cornaciu

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3 August 2017

language of work or name

English

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publication date

25 September 2014

1 reference

Journal of Biological Chemistry

3 August 2017

language of work

1 reference

3 August 2017

volume

289

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3 August 2017

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3 August 2017

page(s)

32559-32570

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G0/G1 switch gene 2 has a critical role in adipocyte differentiation.

3 August 2017

cites work

1 reference

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Mice lacking G0S2 are lean and cold-tolerant

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7 July 2018

Measurement of lipolysis

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Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

7 July 2018

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Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation

7 July 2018

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Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2).

7 July 2018

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Combinatorial peptide libraries: mining for cell-binding peptides

7 July 2018

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Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis

7 July 2018

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G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol

7 July 2018

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Development of small-molecule inhibitors targeting adipose triglyceride lipase

7 July 2018

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The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism

7 July 2018

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G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

7 July 2018

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The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells

7 July 2018

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Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

7 July 2018

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The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively

7 July 2018

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Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes

7 July 2018

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7 July 2018

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Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

7 July 2018

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Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

7 July 2018

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Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2.

7 July 2018

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Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue

7 July 2018

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Lipid-induced insulin resistance: unravelling the mechanism

7 July 2018

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Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae

7 July 2018

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Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

7 July 2018

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The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase

7 July 2018

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The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase

7 July 2018

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Lipid homeostasis, lipotoxicity and the metabolic syndrome.

7 July 2018

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Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists

7 July 2018

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7 July 2018

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Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling

7 July 2018

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Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2

7 July 2018

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7 July 2018

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7 July 2018

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Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

7 July 2018

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Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

7 July 2018

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TXNIP regulates peripheral glucose metabolism in humans

7 July 2018

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Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients.

7 July 2018

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Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

The G0/G1 switch gene 2 is a novel PPAR target gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Reversal of obesity by targeted ablation of adipose tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

The determination of enzyme inhibitor constants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Adipose triglyceride lipase and G0/G1 switch gene 2: approaching proof of concept.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

A novel clinical entity: triglyceride deposit cardiomyovasculopathy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M114.602599

Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4239610

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

27 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.602599

Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches

21 January 2018

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12 December 2020

Inhibition of the hormone-sensitive lipase in adipose tissue by long-chain fatty acyl coenzyme A

1 reference

12 December 2020

Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells

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12 December 2020

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

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12 December 2020

Identifiers

DOI

10.1074/JBC.M114.602599

1 reference

3 August 2017

1 reference

3 August 2017

1 reference