IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP (Q34550996)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP (English)

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2 April 2020

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2 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

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2 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

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2 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Jacob Giehm Mikkelsen

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2 April 2020

K L Jønsson

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2 April 2020

A Laustsen

1 reference

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2 April 2020

C Krapp

1 reference

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2 April 2020

K Thavachelvam

1 reference

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2 April 2020

D Hotter

1 reference

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2 April 2020

M Kjolby

1 reference

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2 April 2020

L K Sørensen

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2 April 2020

C Sun

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2 April 2020

S B Jensen

1 reference

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2 April 2020

R J Lebbink

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2 April 2020

F Kirchhoff

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2 April 2020

S R Paludan

1 reference

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2 April 2020

M R Jakobsen

1 reference

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2 April 2020

language of work or name

English

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publication date

10 February 2017

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2 April 2020

published in

Nature Communications

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volume

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2 April 2020

page(s)

14391

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Creative Commons Attribution 4.0 International

2 April 2020

start time

10 February 2017

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5309897/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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7 July 2018

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7 July 2018

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7 July 2018

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Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

7 July 2018

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7 July 2018

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Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

7 July 2018

1 reference

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Structural mechanism of cytosolic DNA sensing by cGAS

7 July 2018

1 reference

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cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

7 July 2018

1 reference

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The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

STING recognition of cytoplasmic DNA instigates cellular defense

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Preferential binding of IFI16 protein to cruciform structure and superhelical DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

IFI16 is an innate immune sensor for intracellular DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

Amelioration of psoriasis by anti-TNF-alpha RNAi in the xenograft transplantation model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309897

7 July 2018

Identifiers

DOI

10.1038/NCOMMS14391

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 April 2020

ADS bibcode

2017NatCo...814391J

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

PubMed publication ID

28186168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186168%20AND%20SRC:MED&resulttype=core&format=json