Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances (Q34534907)

2 August 2017

1 reference

title

Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances (English)

1 reference

2 August 2017

1 reference

Patel RN

1 reference

2 August 2017

publication date

1 December 2001

1 reference

Current Opinion in Biotechnology

2 August 2017

published in

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

2 August 2017

page(s)

587-604

1 reference

FDA's policy statement for the development of new stereoisomeric drugs

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Biocatalysis for pharmaceuticals--status and prospects for a key technology

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Dehydrogenases and transaminases in asymmetric synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Industrial biocatalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Stereoselective biotransformations in synthesis of some pharmaceutical intermediates.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

An efficient enantioselective synthesis of ( R,R )-formoterol, a potent bronchodilator, using lipases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Antihypertensive activity during inhibition of neutral endopeptidase and angiotensin converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Enzymatic synthesis of L-6-hydroxynorleucine

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Chemical synthesis of allysine ethylene acetal and conversion in situ into 1-piperideine-6-carboxylic acid: key intermediate of the alpha-aminoadipic acid for beta-lactam antibiotics biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Synthesis of allysine ethylene acetal using phenylalanine dehydrogenase from Thermoactinomyces intermedius

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Purification and Properties of Formaldehyde Dehydrogenase and Formate Dehydrogenase from Candida boidinii

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

NAD-linked formate dehydrogenase from methanol-grown Pichia pastoris NRRL-Y-7556

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Biocatalytic preparation of a chiral synthon for a vasopeptidase inhibitor: enzymatic conversion of N(2)-

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Metabolic engineering and directed evolution for the production of pharmaceuticals

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Directed evolution of toluene dioxygenase from Pseudomonas putida for improved selectivity toward cis-indandiol during indene bioconversion

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Regioselective enzymatic aminoacylation of lobucavir to give an intermediate for lobucavir prodrug

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Asymmetric microbial hydrolysis of epoxides

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Dynamic resolution and stereoinversion of secondary alcohols by chemo-enzymatic processes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Application of alpha-keto acid decarboxylases in biotransformations

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Benzoylformate decarboxylase from Pseudomonas putida as stable catalyst for the synthesis of chiral 2-hydroxy ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Tour de paclitaxel: biocatalysis for semisynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Enzymatic kinetic resolution of piperidine atropisomers: synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Structure of an antitumor antibiotic, spergualin

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

Synthesis and antitumor activity of spergualin analogues. III. Novel method for synthesis of optically active 15-deoxyspergualin and 15-deoxy-11-O-methylspergualin

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900266-X

7 January 2021

10.1016/S0958-1669(01)00266-X

Identifiers

DOI

1 reference

2 August 2017

1 reference