DNA double-strand break repair from head to tail (Q34525927)

2 August 2017

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title

DNA double-strand break repair from head to tail (English)

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2 August 2017

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2 August 2017

Christopher D Putnam

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2 August 2017

John A Tainer

series ordinal

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2 August 2017

publication date

1 February 2002

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Current Opinion in Structural Biology

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

115-122

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DNA double-strand breaks: signaling, repair and the cancer connection

2 August 2017

cites work

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7 January 2021

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

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7 January 2021

DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination

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7 January 2021

V(D)J recombination: links to transposition and double-strand break repair.

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7 January 2021

Mating-type gene switching in Saccharomyces cerevisiae

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7 January 2021

Partners and pathwaysrepairing a double-strand break.

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7 January 2021

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

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7 January 2021

Crystal structure of an Xrcc4-DNA ligase IV complex

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7 January 2021

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

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7 January 2021

Conserved domains in DNA repair proteins and evolution of repair systems

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7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

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7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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7 January 2021

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity

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7 January 2021

RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control

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7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

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7 January 2021

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

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7 January 2021

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

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7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

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7 January 2021

The many interfaces of Mre11

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7 January 2021

A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis

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7 January 2021

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

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7 January 2021

Functions of the yeast meiotic recombination genes, MRE11 and MRE2.

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7 January 2021

Complex formation and functional versatility of Mre11 of budding yeast in recombination

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7 January 2021

Chk2 activation dependence on Nbs1 after DNA damage

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7 January 2021

The yeast Xrs2 complex functions in S phase checkpoint regulation

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7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

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7 January 2021

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

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7 January 2021

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

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7 January 2021

Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events

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7 January 2021

RAD50 function is essential for telomere maintenance in Arabidopsis.

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7 January 2021

Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae

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7 January 2021

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

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7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

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7 January 2021

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

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7 January 2021

The role of Schizosaccharomyces pombe Rad32, the Mre11 homologue, and other DNA damage response proteins in non-homologous end joining and telomere length maintenance

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7 January 2021

mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis

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7 January 2021

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1 reference

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7 January 2021

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

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7 January 2021

DNA cleavage and degradation by the SbcCD protein complex from Escherichia coli

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7 January 2021

Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine

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7 January 2021

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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7 January 2021

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

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7 January 2021

DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex

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7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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7 January 2021

Overexpression, purification, and characterization of the SbcCD protein from Escherichia coli.

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7 January 2021

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

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7 January 2021

A mechanistic basis for Mre11-directed DNA joining at microhomologies

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7 January 2021

Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

DNA end-joining: from yeast to man

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Genomic integrity and the repair of double-strand DNA breaks

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

How to make ends meet in V(D)J recombination

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Identification of bacterial homologues of the Ku DNA repair proteins

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https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2802%2900297-X

7 January 2021

10.1016/S0959-440X(02)00297-X

Identifiers

DOI

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2 August 2017

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