Molecular pathways of anxiety revealed by knockout mice (Q34510367)

2 August 2017

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title

Molecular pathways of anxiety revealed by knockout mice (English)

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2 August 2017

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Wood SJ

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2 August 2017

Toth M

series ordinal

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2 August 2017

publication date

1 April 2001

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2 August 2017

published in

Molecular Neurobiology

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2 August 2017

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2 August 2017

issue

2-3

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2 August 2017

page(s)

101-119

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The multifunctional calcium/calmodulin-dependent protein kinase: from form to function

2 August 2017

cites work

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12 December 2020

Transcription factors responsive to cAMP

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12 December 2020

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

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12 December 2020

Increased fearfulness of Fyn tyrosine kinase deficient mice

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12 December 2020

Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour

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12 December 2020

D3 Dopamine Receptor-Deficient Mouse: Evidence for Reduced Anxiety

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12 December 2020

Behavioral characterization of mdx3cv mice deficient in C-terminal dystrophins

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12 December 2020

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

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12 December 2020

Understanding the molecular basis of fragile X syndrome

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12 December 2020

Corticotropin releasing factor produces behavioural activation in rats

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12 December 2020

Nicotinic receptor agonists exhibit anxiolytic-like effects on the elevated plus-maze test

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12 December 2020

Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains

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12 December 2020

Neurotransmission in the rat amygdala related to fear and anxiety

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12 December 2020

Regulation of anxiety by GABAA receptors in the rat amygdala

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12 December 2020

Effects of a microinjection of morphine into the amygdala on the acquisition and expression of conditioned fear and hypoalgesia in rats

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12 December 2020

The neurokinin-1 receptor antagonist WIN51,708 attenuates the anxiolytic-like effects of ventralpallidal substance P injection

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12 December 2020

The influence of a targeted deletion of the IFNgamma gene on emotional behaviors

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12 December 2020

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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12 December 2020

5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions

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12 December 2020

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid

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12 December 2020

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

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12 December 2020

Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECT

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12 December 2020

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior.

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12 December 2020

Altered stress-induced anxiety in adenylyl cyclase type VIII-deficient mice.

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12 December 2020

NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)

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12 December 2020

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

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12 December 2020

Increased anxiety of mice lacking the serotonin1A receptor

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12 December 2020

The noradrenergic system in pathological anxiety: a focus on panic with relevance to generalized anxiety and phobias

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12 December 2020

Molecular and neuronal substrate for the selective attenuation of anxiety.

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12 December 2020

Noradrenergic mechanisms in stress and anxiety: II. Clinical studies

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12 December 2020

Behaviour of the transgenic (mREN2)27 rat.

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12 December 2020

The effects of ICV-CRH on novelty-induced behavior

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12 December 2020

Neurotransmitter functions of mammalian tachykinins

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12 December 2020

Thigmotaxis as a test for anxiolytic activity in rats

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12 December 2020

The neuroanatomical basis of anxiety

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12 December 2020

Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior

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12 December 2020

The use of a plus-maze to measure anxiety in the mouse

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12 December 2020

Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression

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12 December 2020

The postsynaptic density at glutamatergic synapses

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12 December 2020

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

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12 December 2020

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

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12 December 2020

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

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12 December 2020

Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides

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12 December 2020

The 5'-flanking region of the mouse adenylyl cyclase type VIII gene imparts tissue-specific expression in transgenic mice.

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12 December 2020

Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice

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12 December 2020

Animal models of anxiety based on classical conditioning: the conditioned emotional response (CER) and the fear-potentiated startle effect

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12 December 2020

Restraint-stress-induced changes in exploratory behavior appear to be mediated by norepinephrine-stimulated release of CRF.

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12 December 2020

Neuropeptide Y selectively inhibits slow synaptic potentials in rat dorsal raphe nucleus in vitro by a presynaptic action

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12 December 2020

NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats

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12 December 2020

Altered emotional and locomotor responses in mice deficient in the transcription factor CREM

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12 December 2020

Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models

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12 December 2020

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

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12 December 2020

Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations.

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12 December 2020

Measurement of anxiety in transgenic mice.

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12 December 2020

Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines

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12 December 2020

Presynaptic serotonin receptors in the central nervous system

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12 December 2020

Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

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12 December 2020

Mechanisms of emotional arousal and lasting declarative memory.

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12 December 2020

Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II.

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12 December 2020

Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

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12 December 2020

Learning and anxiety in angiotensin-deficient mice

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12 December 2020

Analysis of NMDA receptor mediated synaptic plasticity using gene targeting: roles of Fyn and FAK non-receptor tyrosine kinases.

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12 December 2020

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

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12 December 2020

Activating and 'anxiogenic' effects of corticotropin releasing factor are not inhibited by blockade of the pituitary-adrenal system with dexamethasone

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12 December 2020

Glucocorticoid signalling--multiple variations of a common theme

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12 December 2020

Urocortin, a novel neuropeptide with anxiogenic-like properties

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12 December 2020

Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of Acra7-deficient mice.

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12 December 2020

Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2.

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12 December 2020

Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene

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12 December 2020

5-HT and anxiety: promises and pitfalls

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12 December 2020

Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons

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12 December 2020

Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder

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12 December 2020

Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice

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12 December 2020

Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse

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12 December 2020

Fyn tyrosine kinase participates in the compact myelin sheath formation in the central nervous system

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12 December 2020

The actions of nicotine and cocaine in a mouse model of anxiety

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12 December 2020

Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report

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12 December 2020

Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

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12 December 2020

Anxiolytic-like effect of the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA) on rat exploratory activity

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12 December 2020

The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals

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12 December 2020

Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2.

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12 December 2020

Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus

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12 December 2020

Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

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12 December 2020

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

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12 December 2020

Effect of serotonin inhibition on glucocorticoid and mineralocorticoid expression in various brain structures

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12 December 2020

GABAergic influences on plus-maze behaviour in mice

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12 December 2020

Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons

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12 December 2020

Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses

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12 December 2020

Animal models of 'anxiety': where next?

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12 December 2020

The neurobiology of duchenne muscular dystrophy: learning lessons from muscle?

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12 December 2020

Emotion circuits in the brain

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12 December 2020

Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

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12 December 2020

Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors

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12 December 2020

Mice lacking PKC gamma exhibit decreased anxiety

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12 December 2020

Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors

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12 December 2020

Overexpression of proenkephalin in the amygdala potentiates the anxiolytic effects of benzodiazepines

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12 December 2020

Maudsley reactive and non-reactive rats differ in exploratory behavior but not in learning.

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12 December 2020

Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety

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12 December 2020

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin

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12 December 2020

Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors

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12 December 2020

Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis

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12 December 2020

Effects of sequential removal of rats from a group cage, and of individual housing of rats, on substance P, cholecystokinin and somatostatin levels in the periaqueductal grey and limbic regions

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12 December 2020

Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice

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12 December 2020

Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies

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12 December 2020

5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze.

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12 December 2020

Physiopharmacological interactions between stress hormones and central serotonergic systems

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12 December 2020

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress.

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12 December 2020

Anxiogenic effects of methyl-beta-carboline-3-carboxylate in a light/dark choice situation.

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12 December 2020

Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues

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12 December 2020

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

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12 December 2020

Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli.

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12 December 2020

Apolipoprotein E Binds to and Potentiates the Biological Activity of Ciliary Neurotrophic Factor

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12 December 2020

CCK in anxiety and cognitive processes

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12 December 2020

Animal models for predicting clinical efficacy of anxiolytic drugs: social behaviour

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12 December 2020

Is there a future for neuropeptide receptor ligands in the treatment of anxiety disorders?

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12 December 2020

Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1.

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12 December 2020

The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety

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12 December 2020

Anxiety-like behavior in transgenic mice with brain expression of neuropeptide Y.

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12 December 2020

(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

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12 December 2020

Behavioral characterization of neuropeptide Y knockout mice

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12 December 2020

5-HT1B receptor knock out--behavioral consequences

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12 December 2020

Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests

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12 December 2020

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

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12 December 2020

Identifiers

DOI

10.1385/MN:23:2-3:101

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Dimensions Publication ID

2 August 2017

1041374170

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