Pharmacological inhibitors of MAPK pathways. (Q34502720)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11804650%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

review article

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title

Pharmacological inhibitors of MAPK pathways (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11804650%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11804650%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Jessie M English

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6 December 2019

publication date

1 January 2002

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Trends in Pharmacological Sciences

6 December 2019

published in

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6 December 2019

volume

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6 December 2019

issue

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6 December 2019

page(s)

40-45

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

6 December 2019

cites work

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7 January 2021

Signal transduction through MAP kinase cascades

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7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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7 January 2021

Initial sequencing and analysis of the human genome

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7 January 2021

The Sequence of the Human Genome

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7 January 2021

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

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7 January 2021

Inhibition of p38 MAP kinase as a therapeutic strategy

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7 January 2021

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

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7 January 2021

RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency

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7 January 2021

SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors

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7 January 2021

How MAP kinases are regulated

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7 January 2021

Active and inactive protein kinases: structural basis for regulation

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7 January 2021

Structural analysis of receptor tyrosine kinases

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7 January 2021

Crystal structure of p38 mitogen-activated protein kinase

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7 January 2021

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

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7 January 2021

Structural basis of inhibitor selectivity in MAP kinases

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7 January 2021

The SHAPES strategy: an NMR-based approach for lead generation in drug discovery.

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7 January 2021

Consensus scoring: A method for obtaining improved hit rates from docking databases of three-dimensional structures into proteins.

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7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

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7 January 2021

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

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7 January 2021

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase

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7 January 2021

Molecular basis for p38 protein kinase inhibitor specificity

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7 January 2021

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

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7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

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7 January 2021

Effect of SB 203580 on the activity of c-Raf in vitro and in vivo

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7 January 2021

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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7 January 2021

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

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7 January 2021

The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding

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7 January 2021

Kinetic mechanism and ATP-binding site reactivity of p38gamma MAP kinase

1 reference

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7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

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7 January 2021

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

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7 January 2021

Development of anticancer drugs targeting the MAP kinase pathway

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7 January 2021

Pharmacologic inhibitors of MKK1 and MKK2.

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7 January 2021

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

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7 January 2021

Differential MAPK pathways utilized for HGF- and EGF-dependent renal epithelial morphogenesis

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7 January 2021

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

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7 January 2021

Direct Inhibition of Cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059

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7 January 2021

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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7 January 2021

Synthesis and structure-activity relationships of 3-cyano-4-(phenoxyanilino)quinolines as MEK (MAPKK) inhibitors

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7 January 2021

Ro 09-2210 exhibits potent anti-proliferative effects on activated T cells by selectively blocking MKK activity

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7 January 2021

Resorcylic acid lactones: naturally occurring potent and selective inhibitors of MEK

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7 January 2021

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7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

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7 January 2021

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

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7 January 2021

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

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7 January 2021

The discovery of potent cRaf1 kinase inhibitors

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7 January 2021

10.1016/S0165-6147(00)01865-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11804650%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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