High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation (Q34482369)

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English	High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation (English)

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PubMed publication ID

2 August 2017

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author name string

Audrey D McConnell

1

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2 August 2017

Minjee Do

2

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2 August 2017

Tamlyn Y Neben

3

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2 August 2017

Vladimir Spasojevic

4

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2 August 2017

Josh MacLaren

5

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2 August 2017

Andy P Chen

6

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2 August 2017

Laurence Altobell

7

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2 August 2017

John L Macomber

8

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2 August 2017

Ashley D Berkebile

9

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2 August 2017

Robert A Horlick

10

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2 August 2017

Peter M Bowers

11

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2 August 2017

David J King

12

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2 August 2017

language of work or name

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publication date

14 November 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

11

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2 August 2017

e49458

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Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

14 November 2012

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April 2022 Public Data File from Crossref

copyright status

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Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3498135

6 July 2018

Identification of a central role for complement in osteoarthritis

1 reference

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6 July 2018

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

1 reference

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6 July 2018

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

1 reference

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6 July 2018

Humanization of antibodies.

1 reference

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6 July 2018

Clinical development of anti-RANKL therapy

1 reference

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6 July 2018

Potent antibody therapeutics by design

1 reference

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6 July 2018

Human antibodies from transgenic animals

1 reference

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6 July 2018

Selecting and screening recombinant antibody libraries

1 reference

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6 July 2018

Functional insights from the structure of the multifunctional C345C domain of C5 of complement

1 reference

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6 July 2018

Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas

1 reference

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6 July 2018

Antibody multispecificity mediated by conformational diversity

1 reference

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6 July 2018

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

1 reference

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6 July 2018

Targeting vectors for intracellular immunisation.

1 reference

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6 July 2018

Anatomy of the antibody molecule

1 reference

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6 July 2018

The membrane attack complex of complement

1 reference

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6 July 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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6 July 2018

V(D)J recombination: molecular biology and regulation

1 reference

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6 July 2018

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

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6 July 2018

Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.

1 reference

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21 January 2018

Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis.

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21 January 2018

Somatic insertions and deletions shape the human antibody repertoire

1 reference

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21 January 2018

Secretion from bacterial versus mammalian cells yields a recombinant scFv with variable folding properties.

1 reference

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27 October 2018

A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants

1 reference

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12 December 2020

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A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis

1 reference

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Effects of an anti-TNF-alpha monoclonal antibody, administered throughout pregnancy and lactation, on the development of the macaque immune system

1 reference

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Identifiers

10.1371/JOURNAL.PONE.0049458

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Europe PubMed Central

PubMed publication ID

2 August 2017

2012PLoSO...749458M

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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