TP53 loss creates therapeutic vulnerability in&#160;colorectal cancer (Q34473071)

25901683

2 August 2017

title

TP53 loss creates therapeutic vulnerability in colorectal cancer (English)

1 reference

2 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25901683%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25901683%20AND%20SRC:MED&resulttype=core&format=json

Cristian Rodriguez-Aguayo

10 June 2020

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10 June 2020

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10 June 2020

Xinna Zhang

1 reference

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10 June 2020

Anil K Sood

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10 June 2020

Gabriel Lopez-Berestein

object named as

Gabriel Lopez-Berestein

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10 June 2020

Yunhua Liu

1 reference

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10 June 2020

Cecil Han

1 reference

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10 June 2020

Xingxu Huang

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10 June 2020

Dahai Jiang

1 reference

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10 June 2020

Pulivarthi H Rao

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10 June 2020

Dipen M Maru

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10 June 2020

Andreas Pahl

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10 June 2020

Lee M Ellis

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10 June 2020

Jan Anderl

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10 June 2020

Xiongbin Lu

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10 June 2020

language of work or name

English

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publication date

22 April 2015

1 reference

2 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25901683%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

520

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10 June 2020

issue

7549

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10 June 2020

page(s)

697-701

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Therapeutic silencing of KRAS using systemically delivered siRNAs

10 June 2020

cites work

1 reference

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Genetic screens in human cells using the CRISPR-Cas9 system

6 July 2018

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6 July 2018

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

6 July 2018

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Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1.

6 July 2018

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MDM2, MDMX and p53 in oncogenesis and cancer therapy

6 July 2018

1 reference

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Multiplex genome engineering using CRISPR/Cas systems

6 July 2018

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Cancer vulnerabilities unveiled by genomic loss

6 July 2018

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Passenger deletions generate therapeutic vulnerabilities in cancer

6 July 2018

1 reference

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Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma

6 July 2018

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Kaposi's sarcoma-associated herpesvirus-encoded microRNA miR-K12-11 attenuates transforming growth factor beta signaling through suppression of SMAD5.

6 July 2018

1 reference

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Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?

6 July 2018

1 reference

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Translating p53 into the clinic.

6 July 2018

1 reference

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Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies

6 July 2018

1 reference

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A rapid and general assay for monitoring endogenous gene modification

6 July 2018

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6 July 2018

p53-based cancer therapy

1 reference

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Genomic instability--an evolving hallmark of cancer

6 July 2018

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The genetics of the p53 pathway, apoptosis and cancer therapy

6 July 2018

1 reference

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RPA and ATR link transcriptional stress to p53

6 July 2018

1 reference

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

6 July 2018

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Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

6 July 2018

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Molecular characterization and inhibition of amanitin uptake into human hepatocytes

6 July 2018

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Manipulation of the tumor suppressor p53 for potentiating cancer therapy

6 July 2018

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Frequent EpCam protein expression in human carcinomas

6 July 2018

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Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

6 July 2018

1 reference

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Protein conjugates of fungal toxins

6 July 2018

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Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25901683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE14418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25901683%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

0 references

1 reference

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10 June 2020

25901683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25901683%20AND%20SRC:MED&resulttype=core&format=json