Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways (Q34464791)

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English	Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

endoplasmic reticulum

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reperfusion injury

1 reference

based on heuristic

inferred from title

author name string

Yapeng Li

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Wei Zhu

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

Jianping Tao

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Ping Xin

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Mingya Liu

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Jingbo Li

6

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Europe PubMed Central

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2 August 2017

Meng Wei

7

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

31 October 2012

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Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

e48115

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

31 October 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins

1 reference

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6 July 2018

Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart.

1 reference

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6 July 2018

SERCA1 expression enhances the metabolic efficiency of improved contractility in post-ischemic heart

1 reference

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6 July 2018

Targeting calcium transport in ischaemic heart disease.

1 reference

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Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?

1 reference

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6 July 2018

Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury.

1 reference

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6 July 2018

Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?

1 reference

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Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition

1 reference

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6 July 2018

Oxidative injury induces selective rather than global inhibition of proteasomal activity

1 reference

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6 July 2018

A molecular chaperone inducer protects neurons from ER stress

1 reference

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6 July 2018

Endoplasmic reticulum stress in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3485283

6 July 2018

Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat.

1 reference

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6 July 2018

ER stress contributes to ischemia-induced cardiomyocyte apoptosis

1 reference

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6 July 2018

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

1 reference

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6 July 2018

Cardioprotective effect of hydroxyfasudil as a specific Rho-kinase inhibitor, on ischemia-reperfusion injury in canine coronary microvessels in vivo.

1 reference

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6 July 2018

Cellular response to endoplasmic reticulum stress: a matter of life or death

1 reference

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

1 reference

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6 July 2018

Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death

1 reference

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Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.

1 reference

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Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

1 reference

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New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

1 reference

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The first minutes of reperfusion: a window of opportunity for cardioprotection

1 reference

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Overexpression of the stress protein Grp94 reduces cardiomyocyte necrosis due to calcium overload and simulated ischemia

1 reference

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Orchestrating the unfolded protein response in health and disease

1 reference

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6 July 2018

The sarco/endoplasmic reticulum calcium-ATPase 2b is an endoplasmic reticulum stress-inducible protein

1 reference

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6 July 2018

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

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Changes in endoplasmic reticulum Ca(2-)-ATPase mRNA levels in transient cerebral ischemia of rat: a quantitative polymerase chain reaction study

1 reference

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Inhibition of endoplasm reticulum stress by ghrelin protects against ischemia/reperfusion injury in rat heart.

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A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases

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Stimulation of cGMP signalling protects coronary endothelium against reperfusion-induced intercellular gap formation

1 reference

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Apelin-13 protects the heart against ischemia-reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion.

1 reference

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Administration of the Rho-kinase inhibitor fasudil before ischemia or just after reperfusion, but not 30 min after reperfusion, protects the stunned myocardium in swine

1 reference

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21 January 2018

Combined local ischemic postconditioning and remote perconditioning recapitulate cardioprotective effects of local ischemic preconditioning

1 reference

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Calpain activation contributes to hyperglycaemia-induced apoptosis in cardiomyocytes.

1 reference

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21 January 2018

Effect of ischemia and reperfusion on cardiac ryanodine receptors--sarcoplasmic reticulum Ca2+ channels.

1 reference

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Effects of resveratrol on calcium regulation in rats with severe acute pancreatitis

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21 January 2018

Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

21 January 2018

Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

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Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans

1 reference

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Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

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Ischemic postconditioning protects myocardium from ischemia/reperfusion injury through attenuating endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

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Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

21 January 2018

Ischemic postconditioning in pigs: no causal role for RISK activation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

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S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

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Ca2+ transport ATPase isoforms SERCA2a and SERCA2b are targeted to the same sites in the murine heart.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048115

21 January 2018

Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

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Myocardial reperfusion injury: a new view

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional reconstitution of the cardiac sarcoplasmic reticulum Ca2(+)-ATPase with phospholamban in phospholipid vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin protects cardiomyocytes against reoxygenation-induced hypercontracture by a survival pathway targeting SR Ca2+ storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term inhibition of myocardial infarction by postconditioning during reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tight interplay between the Ca2+ affinity of the cardiac SERCA2 Ca2+ pump and the SERCA2 expression level

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

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inferred from PubMed ID database lookup

Low dose cyclophosphamide rescues myocardial function from ischemia-reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118936

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Identifiers

10.1371/JOURNAL.PONE.0048115

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2012PLoSO...748115L

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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