Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? (Q34455538)

2 August 2017

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title

Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? (English)

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2 August 2017

Weiler J

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2 August 2017

Hunziker J

series ordinal

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2 August 2017

Hall J

series ordinal

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2 August 2017

publication date

1 March 2006

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

496-502

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The functions of animal microRNAs

2 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

MicroRNAs: genomics, biogenesis, mechanism, and function

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Post-transcriptional gene silencing by siRNAs and miRNAs

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MicroRNA biogenesis: coordinated cropping and dicing

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MicroRNA maturation: stepwise processing and subcellular localization

21 January 2018

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

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MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

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Nuclear export of microRNA precursors

21 January 2018

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Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

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siRNA and miRNA: an insight into RISCs

21 January 2018

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MicroRNA-directed cleavage of HOXB8 mRNA

21 January 2018

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21 January 2018

The microRNA Registry

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

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MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

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MicroRNA-143 regulates adipocyte differentiation

21 January 2018

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A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

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MicroRNA biogenesis and cancer

21 January 2018

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Numerous microRNPs in neuronal cells containing novel microRNAs

21 January 2018

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Identification of virus-encoded microRNAs

21 January 2018

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21 January 2018

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The role of small RNAs in human diseases: potential troublemaker and therapeutic tools

21 January 2018

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

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RAS is regulated by the let-7 microRNA family

21 January 2018

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Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

21 January 2018

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High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

21 January 2018

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Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

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A microRNA polycistron as a potential human oncogene

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells

21 January 2018

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Identification of microRNAs of the herpesvirus family

21 January 2018

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Regulation of human immunodeficiency virus 1 transcription by nef microRNA.

21 January 2018

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SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

HIV-1 nef suppression by virally encoded microRNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

A cellular microRNA mediates antiviral defense in human cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Intramers and aptamers: applications in protein-function analyses and potential for drug screening

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

RNA and microRNAs in fragile X mental retardation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

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Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway

21 January 2018

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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

21 January 2018

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The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

21 January 2018

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MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

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Potential applications of siRNA for pain therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation

21 January 2018

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Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes

21 January 2018

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Sequence-specific inhibition of small RNA function

21 January 2018

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In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors

21 January 2018

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Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Antisense therapy for cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Single nucleotide polymorphism genotyping using locked nucleic acid (LNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Incorporating structure to predict microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

21 January 2018

Human MicroRNA targets

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Combinatorial microRNA target predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

Polymorphisms in human pre-miRNAs

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing.

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

The age of high-throughput microRNA profiling

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

Silence is golden: can RNA interference therapeutics deliver?

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302654

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302654

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Dimensions Publication ID

2 August 2017

1022653137

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