Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs (Q34448305)

2 August 2017

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title

Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs (English)

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2 August 2017

Patel J

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2 August 2017

Mitra AK

series ordinal

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2 August 2017

publication date

1 November 2001

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

401-415

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Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism

2 August 2017

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21 January 2018

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Epithelial secretion of vinblastine by human intestinal adenocarcinoma cell (HCT-8 and T84) layers expressing P-glycoprotein

21 January 2018

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Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

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The human hepatic cytochromes P450 involved in drug metabolism

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21 January 2018

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HIV protease inhibitors: advances in therapy and adverse reactions, including metabolic complications

21 January 2018

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Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction

21 January 2018

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The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin

21 January 2018

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Reversal of drug resistance by erythromycin: erythromycin increases the accumulation of actinomycin D and doxorubicin in multidrug-resistant cells.

21 January 2018

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Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue

21 January 2018

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21 January 2018

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Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

21 January 2018

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Interaction between grapefruit juice and midazolam in humans*

21 January 2018

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Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

21 January 2018

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Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

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Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 January 2018

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

21 January 2018

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CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

21 January 2018

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Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

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Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

21 January 2018

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Cyclosporins as drug resistance modifiers

21 January 2018

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Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.

21 January 2018

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Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

21 January 2018

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Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

21 January 2018

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Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein

21 January 2018

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Staurosporine reduces P-glycoprotein expression and modulates multidrug resistance.

21 January 2018

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Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein

21 January 2018

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Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

21 January 2018

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Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

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21 January 2018

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Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody

21 January 2018

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Modulation of MDR1 and CYP3A expression by dexamethasone: evidence for an inverse regulation in adrenals

21 January 2018

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Phenobarbital induction of cytochromes P-450. High-level long-term responsiveness of primary rat hepatocyte cultures to drug induction, and glucocorticoid dependence of the phenobarbital response

21 January 2018

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21 January 2018

HIV-protease inhibitors

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Grapefruit juice and drugs. How significant is the interaction?

21 January 2018

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Interaction of citrus juices with felodipine and nifedipine

21 January 2018

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Influence of chronic ingestion of grapefruit juice on steady-state blood concentrations of cyclosporine A in renal transplant patients with stable graft function

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.2.4.401

Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins

21 January 2018

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Biological effects of resveratrol

21 January 2018

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Resveratrol: a molecule whose time has come? And gone?

21 January 2018

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Resveratrol, a red wine constituent, is a mechanism-based inactivator of cytochrome P450 3A4.

21 January 2018

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

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Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/BPB.21.1062

Identifiers

DOI

10.1517/14622416.2.4.401

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2 August 2017

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