Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. (Q34424993)

2 August 2017

title

Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. (English)

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2 August 2017

J L Goldstein

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2 August 2017

E A Duncan

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2 August 2017

M S Brown

series ordinal

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2 August 2017

J Sakai

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 May 1997

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Journal of Biological Chemistry

2 August 2017

published in

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2 August 2017

volume

272

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2 August 2017

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2 August 2017

page(s)

12778-12785

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

2 August 2017

cites work

1 reference

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Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

21 January 2018

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Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

21 January 2018

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Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection

21 January 2018

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SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

21 January 2018

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SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

21 January 2018

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A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene

21 January 2018

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Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene

21 January 2018

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Molecular Cloning and Functional Analysis of the Promoter of the Human Squalene Synthase Gene

21 January 2018

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ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

21 January 2018

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Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways

21 January 2018

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

21 January 2018

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Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

21 January 2018

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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

21 January 2018

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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

21 January 2018

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Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

21 January 2018

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The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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A mechanism by which adenovirus virus-associated RNAI controls translation in a transient expression assay

21 January 2018

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Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia

21 January 2018

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In vitro selection of an RNA epitope immunologically cross-reactive with a peptide

21 January 2018

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Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

21 January 2018

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ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

21 January 2018

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HLH106, a Drosophila transcription factor with similarity to the vertebrate sterol responsive element binding protein.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.19.12778

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2 August 2017

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