Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma (Q34414702)

From Wikidata

Jump to navigation Jump to search

scientific article

edit

Language	Label	Description	Also known as
English	Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma	scientific article

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

retrieved

2 August 2017

title

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

retrieved

2 August 2017

author

Elías Campo

series ordinal

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

Dolors Colomer

series ordinal

12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

Gaël Roué

series ordinal

13

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

author name string

A Moros

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

V Rodríguez

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

I Saborit-Villarroya

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

A Montraveta

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

P Balsas

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

P Sandy

series ordinal

6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

A Martínez

series ordinal

7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

A Wiestner

series ordinal

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

E Normant

series ordinal

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

P Pérez-Galán

series ordinal

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

publication date

18 March 2014

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

retrieved

2 August 2017

published in

Leukemia

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

volume

28

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

issue

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

page(s)

2049-2059

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

cites work

The complex landscape of genetic alterations in mantle cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lenalidomide efficacy in activated B-cell-like subtype diffuse large B-cell lymphoma is dependent upon IRF4 and cereblon expression

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of tumor oncogenes by disruption of super-enhancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRF4 is a suppressor of c-Myc induced B cell leukemia.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of BET bromodomain targets genetically diverse glioblastoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathogenesis of mantle cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitors in cancer therapy: lessons from the first decade

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRF4 addiction in multiple myeloma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term follow-up of lenalidomide in relapsed/refractory mantle cell lymphoma: subset analysis of the NHL-003 study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-agent lenalidomide in patients with mantle-cell lymphoma who relapsed or progressed after or were refractory to bortezomib: phase II MCL-001 (EMERGE) study.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of MYC translocations in multiple myeloma cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with chemotherapy-refractory mantle cell lymphoma experience high response rates and identical progression-free survivals compared with patients with relapsed disease following treatment with single agent bortezomib: results of a multicentr

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An international phase II trial of single-agent lenalidomide for relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting MYC dependence in cancer by inhibiting BET bromodomains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vitro Cytotoxicity and In Vivo Efficacy, Pharmacokinetics, and Metabolism of 10074-G5, a Novel Small-Molecule Inhibitor of c-Myc/Max Dimerization

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the ubiquitin proteasome system: beyond proteasome inhibition.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-agent lenalidomide is active in patients with relapsed or refractory aggressive non-Hodgkin lymphoma who received prior stem cell transplantation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer: An unexpected addiction.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A library of gene expression signatures to illuminate normal and pathological lymphoid biology

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24721791

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/LEU.2014.106

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

Dimensions Publication ID

1005697741

0 references

PubMed publication ID

24721791

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24721791

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24721791%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 June 2020

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34414702&oldid=2196603631"