Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism. (Q34401594)

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scientific article published in March 2005

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English	Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism.	scientific article published in March 2005

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scholarly article

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Europe PubMed Central

PMC publication ID

6725172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

title

Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism (English)

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stated in

Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

author name string

Yan Yang

series ordinal

1

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Europe PubMed Central

PMC publication ID

6725172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

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9 January 2020

Karl Herrup

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2

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Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

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9 January 2020

language of work or name

English

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publication date

1 March 2005

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Europe PubMed Central

PMC publication ID

6725172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

published in

Journal of Neuroscience

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stated in

Europe PubMed Central

PMC publication ID

6725172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

volume

25

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Europe PubMed Central

PMC publication ID

6725172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

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9 January 2020

issue

10

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stated in

Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

page(s)

2522-2529

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Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

cites work

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

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Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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inferred from PubMed ID database lookup

Atm-deficient mice Purkinje cells show age-dependent defects in calcium spike bursts and calcium currents

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

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Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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Ataxia telangiectasia mutated is essential during adult neurogenesis

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12 December 2020

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DNA replication precedes neuronal cell death in Alzheimer's disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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Cell cycle checkpoint signaling through the ATM and ATR kinases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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ATM: genome stability, neuronal development, and cancer cross paths

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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Expression patterns of retinoblastoma protein in Parkinson disease

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12 December 2020

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inferred from PubMed ID database lookup

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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12 December 2020

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Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis

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ATM and related protein kinases: safeguarding genome integrity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

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12 December 2020

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Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

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Multiple signaling pathways involving ATM.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

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Late degeneration of nigro-striatal neurons in ATM-/- mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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inferred from PubMed ID database lookup

Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice

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[ON ATAXIA WITH TELANGIECTASIA, AN ANATOMICAL-CLINICAL OBSERVATION]

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal expression of cell cycle-related proteins after brain ischaemia in man.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATM and ataxia telangiectasia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The induction of multiple cell cycle events precedes target-related neuronal death

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dystonia in ataxia telangiectasia: report of a case with putaminal lesions and decreased striatal [123I]iodobenzamide binding

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

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inferred from PubMed ID database lookup

Mitotic mechanisms in Alzheimer's disease?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle markers in the hippocampus in Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxia telangiectasia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATM mutations in B-cell chronic lymphocytic leukemia.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15758161

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.4946-04.2005

1 reference

stated in

Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

PMC publication ID

6725172

1 reference

stated in

Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

PubMed publication ID

15758161

1 reference

stated in

Europe PubMed Central

PMC publication ID

6725172

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758161%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 January 2020

 

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