Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway (Q34400761)

1 August 2017

title

Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway (English)

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ubiquitin-proteasome system

1 August 2017

main subject

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ORCID Public Data File 2021

1 August 2017

Rosanna Piccirillo

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Mikael Altun

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Mariola J Edelmann

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Herman S Overkleeft

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Brun Ulfhake

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author name string

Henrike C Besche

series ordinal

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1 August 2017

Alfred L Goldberg

series ordinal

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1 August 2017

language of work or name

English

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publication date

12 October 2010

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

285

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1 August 2017

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1 August 2017

page(s)

39597-39608

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describes a project that uses

1 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3000941/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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A ubiquitin stress response induces altered proteasome composition.

6 July 2018

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Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins

21 January 2018

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Age-dependent declines in proteasome activity in the heart

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Altered proteasome structure, function, and oxidation in aged muscle

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Behavioral impairments of the aging rat.

21 January 2018

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Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits

21 January 2018

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Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.129718

The synthesis and proteasomal degradation of a model substrate Ub5DHFR.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.129718

Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.129718

Ubiquitin expression is up-regulated in human and rat skeletal muscles during aging

21 January 2018

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Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.129718

Proteasomal activity in brain differs between species and brain regions and changes with age.

21 January 2018

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Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle.

21 January 2018

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Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women

21 January 2018

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VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.129718

Iron load and redox stress in skeletal muscle of aged rats

21 January 2018

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Myofibrillar protein synthesis in young and old men

21 January 2018

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12 December 2020

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12 December 2020

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12 December 2020

Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia

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12 December 2020

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Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

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12 December 2020

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

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12 December 2020

Changes in 20S proteasome activity during ageing of the LOU rat

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Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats

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12 December 2020

Proteolysis: from the lysosome to ubiquitin and the proteasome

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Contributions of the ubiquitin-proteasome pathway and apoptosis to human skeletal muscle wasting with age

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Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.129718

1 reference

1 August 2017

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1 August 2017

1 reference