Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas (Q34397318)

From Wikidata

Jump to navigation Jump to search

scientific article published on November 15, 2010

Language	Label	Description	Also known as
English	Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas	scientific article published on November 15, 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Margaret Porter Scott

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Christopher J. Sneeringer

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

Kevin W. Kuntz

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

Sarah K. Knutson

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

Roy M. Pollock

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

Victoria M. Richon

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

Robert A. Copeland

7

0000-0002-1897-6533

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

language of work or name

0 references

publication date

15 November 2010

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

full work available at URL

https://europepmc.org/articles/pmc3000297?pdf=render

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21078963/pdf/?tool=EBI

Portable Document Format

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21078963/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://europepmc.org/articles/PMC3000297

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://europepmc.org/articles/PMC3000297?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://doi.org/10.1073/pnas.1012525107

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078963

27 August 2024

https://pnas.org/doi/pdf/10.1073/pnas.1012525107

1 reference

10.1073/PNAS.1012525107

https://api.crossref.org/works/10.1073/PNAS.1012525107

27 August 2024

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

107

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

20980-20985

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Targeting epigenetic enzymes for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Structural Biology of Human H3K9 Methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Protein methyltransferases as a target class for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Roles of the EZH2 histone methyltransferase in cancer epigenetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Role of hPHF1 in H3K27 methylation and Hox gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

High-resolution profiling of histone methylations in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Connections between epigenetic gene silencing and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

The SET-domain protein superfamily: protein lysine methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Structure and catalytic mechanism of the human histone methyltransferase SET7/9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

6 July 2018

Deregulation of H3K27 methylation in cancer

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012525107

21 January 2018

Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012525107

21 January 2018

In vivo labeling of fission yeast DNA with thymidine and thymidine analogs

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012525107

21 January 2018

Purification of histone methyltransferases from HeLa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000297

27 October 2018

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EZH2 Mediates DNA Methylation-Independent Epigenetic Silencing of a Germinal Center Specific Transcriptional Program That Contributes to Cellular Proliferation and Lymphomagenesis.

14

1 reference

10.1073/PNAS.1012525107

https://api.crossref.org/works/10.1073/PNAS.1012525107

27 August 2024

Epigenetic approaches to cancer therapy

29

1 reference

10.1073/PNAS.1012525107

https://api.crossref.org/works/10.1073/PNAS.1012525107

27 August 2024

Identifiers

10.1073/PNAS.1012525107

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2010PNAS..10720980S

0 references

release_oekpj3all5ctjlapeovchwxajq

1 reference

https://api.fatcat.wiki/v0/release/oekpj3all5ctjlapeovchwxajq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34397318&oldid=2237426265"