Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM? (Q34383339)

1 August 2017

title

Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM? (English)

1 reference

1 August 2017

1 reference

Rémi Rosière

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Nathalie Wauthoz

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Steven De Vleeschouwer

object named as

Steven de Vleeschouwer

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Matthias van Woensel

1 reference

1 August 2017

Karim Amighi

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1 August 2017

Véronique Mathieu

1 reference

1 August 2017

Florence Lefranc

1 reference

1 August 2017

Stefaan W van Gool

1 reference

1 August 2017

publication date

14 August 2013

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

1020-1048

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Creative Commons Attribution 4.0 International

1 August 2017

start time

14 August 2013

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Characterization of lactoferrin as a targeting ligand for nonviral gene delivery to airway epithelial cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain

6 July 2018

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Medicinal chemical properties of successful central nervous system drugs

6 July 2018

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Claudins and epithelial paracellular transport

6 July 2018

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Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol

6 July 2018

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Nontoxic membrane translocation peptide from protamine, low molecular weight protamine (LMWP), for enhanced intracellular protein delivery: in vitro and in vivo study

6 July 2018

1 reference

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Oxytocin increases trust in humans

6 July 2018

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Glycoconjugate expression in normal human inferior turbinate mucosa: a lectin histochemical study.

6 July 2018

1 reference

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Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species

6 July 2018

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Years of life lost (YLL) from cancer is an important measure of population burden--and should be considered when allocating research funds

6 July 2018

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Information processing in the mammalian olfactory system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Recent advances on chitosan-based micro- and nanoparticles in drug delivery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Oncolytic viruses for treatment of malignant brain tumours.

6 July 2018

1 reference

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5-Fluorouracil: mechanisms of action and clinical strategies

6 July 2018

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Regulated portals of entry into the cell

6 July 2018

1 reference

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Neuroprotective effects of estradiol-17beta: implications for psychiatric disorders

6 July 2018

1 reference

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Local treatment of brain tumors with targeted chimera cytotoxic proteins

6 July 2018

1 reference

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Mutational analysis of ganglioside GM(1)-binding ability, pentamer formation, and epitopes of cholera toxin B (CTB) subunits and CTB/heat-labile enterotoxin B subunit chimeras.

6 July 2018

1 reference

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Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Transport of drugs from the nasal cavity to the central nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Chitosan and its use as a pharmaceutical excipient

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Perivascular spaces in the basal ganglia of the human brain: their relationship to lacunes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors

6 July 2018

1 reference

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Convection-enhanced delivery of macromolecules in the brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Globose basal cells are neuronal progenitors in the olfactory epithelium: a lineage analysis using a replication-incompetent retrovirus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

The fine structure of the olfactory mucosa in man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

6 July 2018

Human respiratory mucus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Fine structural localization of a blood-brain barrier to exogenous peroxidase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Transport of molecules from nose to brain: transneuronal anterograde and retrograde labeling in the rat olfactory system by wheat germ agglutinin-horseradish peroxidase applied to the nasal epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

The relationship between nasal anatomy and human olfaction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

The nasal mucociliary clearance: relevance to nasal drug delivery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Drug metabolism in the nasal mucosa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Morphology of olfactory epithelium in humans and other vertebrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Demonstration of terminalis, olfactory, trigeminal and perivascular nerves in the rat nasal septum

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Counterbalancing risks and gains from extended resections in malignant glioma surgery: a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study. Clinical article

6 July 2018

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Should dendritic cell-based tumor vaccination be incorporated into standard therapy for newly diagnosed glioblastoma patients?

21 January 2018

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Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group

21 January 2018

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Visualization of in vivo olfactory uptake and transfer using fluorescein dextran

21 January 2018

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https://api.crossref.org/works/10.3390%2FCANCERS5031020

The Grueneberg ganglion of the mouse projects axons to glomeruli in the olfactory bulb.

21 January 2018

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THE LYMPHATIC PATHWAY FROM THE NOSE AND PHARYNX : THE ABSORPTION OF DYES.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

The transnasal delivery of 5-fluorouracil to the rat brain is enhanced by acetazolamide (the inhibitor of the secretion of cerebrospinal fluid).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Transnasal delivery of 5-fluorouracil to the brain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Study on brain targeting of raltitrexed following intranasal administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Telomerase activity in human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Distribution and clearance of bioadhesive formulations from the olfactory region in man: effect of polymer type and nasal delivery device

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

The brain targeting efficiency following nasally applied MPEG-PLA nanoparticles in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Lectin-conjugated PEG-PLA nanoparticles: preparation and brain delivery after intranasal administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

UEA I-bearing nanoparticles for brain delivery following intranasal administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Development and evaluation of olanzapine-loaded PLGA nanoparticles for nose-to-brain delivery: In vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Preparation, characterization, in vivo biodistribution and pharmacokinetic studies of donepezil-loaded PLGA nanoparticles for brain targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Enhanced bioavailability of metoclopramide HCl by intranasal administration of a mucoadhesive in situ gel with modulated rheological and mucociliary transport properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Intranasal nanoemulsion based brain targeting drug delivery system of risperidone

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Solid lipid nanoparticles of ondansetron HCl for intranasal delivery: development, optimization and evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Phospholipid based colloidal poloxamer-nanocubic vesicles for brain targeting via the nasal route.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

A study of rivastigmine liposomes for delivery into the brain through intranasal route

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Anxiety and cognitive effects of quercetin liposomes in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Evaluation of the clearance characteristics of various microspheres in the human nose by gamma-scintigraphy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

P-Glycoprotein attenuates brain uptake of substrates after nasal instillation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Evaluation of effect of ephedrine on the transport of drugs from the nasal cavity to the systemic circulation and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Novel vasoconstrictor formulation to enhance intranasal targeting of neuropeptide therapeutics to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Breath actuated device improves delivery to target sites beyond the nasal valve

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Brain delivery of proteins by the intranasal route of administration: a comparison of cationic liposomes versus aqueous solution formulations

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

The relevance to humans of animal models for inhalation studies of cancer in the nose and upper airways.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Conference on obstacles to the control of acute leukemia. Experimental studies of the blood-brain barrier

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795377

Biovector nanoparticles improve antinociceptive efficacy of nasal morphine

27 October 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS5031020

Freeze-fracture and tracer experiments on the permeability of the zonulae occludentes in the olfactory mucosa of vertebrates

21 January 2018

1 reference

12 December 2020

Electron microscopy of the olfactory and gustatory pathways

1 reference

12 December 2020

Ultrastructure of human nasal mucosa

1 reference

12 December 2020

Disposition and metabolism of olanzapine in mice, dogs, and rhesus monkeys

1 reference

12 December 2020

Lectin-binding pattern of neuroepithelial and respiratory epithelial cells in the mouse nasal cavity

1 reference

12 December 2020

Mucoadhesive nanoemulsion-based intranasal drug delivery system of olanzapine for brain targeting

1 reference

12 December 2020

Intranasal drug delivery by spray and drops

1 reference

12 December 2020

Profiles of methotrexate in blood and CSF following intranasal and intravenous administration to rats

1 reference

12 December 2020

Quantitative analysis of the olfactory pathway for drug delivery to the brain

1 reference

12 December 2020

Evaluation of the clearance characteristics of bioadhesive systems in humans

1 reference

12 December 2020

Clearance characteristics of chitosan based formulations in the sheep nasal cavity

1 reference

12 December 2020

Central olfactory connections in the macaque monkey

1 reference

12 December 2020

Identifiers

DOI

10.3390/CANCERS5031020

1 reference

1 August 2017

1 reference

1 August 2017

1 reference