The genomics of schizophrenia: update and implications. (Q34381708)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24177465%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

The genomics of schizophrenia: update and implications (English)

1 reference

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29 February 2020

0 references

0 references

Paola Giusti-Rodríguez

series ordinal

1 reference

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29 February 2020

Patrick F Sullivan

1 reference

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29 February 2020

language of work or name

English

0 references

publication date

1 November 2013

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29 February 2020

number of pages

1 reference

Journal of Clinical Investigation

inferred from page(s)

published in

1 reference

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29 February 2020

volume

123

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29 February 2020

issue

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29 February 2020

page(s)

4557-4563

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Questions about DISC1 as a genetic risk factor for schizophrenia

29 February 2020

cites work

1 reference

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

6 July 2018

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Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network

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Major channels involved in neuropsychiatric disorders and therapeutic perspectives

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6 July 2018

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6 July 2018

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Using summary data from the danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder

6 July 2018

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6 July 2018

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Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders.

6 July 2018

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Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.

6 July 2018

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KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

6 July 2018

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Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.

6 July 2018

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6 July 2018

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CNVs: harbingers of a rare variant revolution in psychiatric genetics

6 July 2018

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6 July 2018

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High frequencies of de novo CNVs in bipolar disorder and schizophrenia

6 July 2018

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De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

6 July 2018

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Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

6 July 2018

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Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability

6 July 2018

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Genome-wide association study identifies five new schizophrenia loci

6 July 2018

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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

6 July 2018

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Signaling complexes of voltage-gated calcium channels

6 July 2018

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Exome sequencing supports a de novo mutational paradigm for schizophrenia.

6 July 2018

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Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

6 July 2018

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6 July 2018

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Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

6 July 2018

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6 July 2018

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Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications

6 July 2018

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Deletion 17q12 Is a Recurrent Copy Number Variant that Confers High Risk of Autism and Schizophrenia

6 July 2018

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6 July 2018

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Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

6 July 2018

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Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

6 July 2018

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Genomic analysis of mental illness: a changing landscape

6 July 2018

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Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies

6 July 2018

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22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

6 July 2018

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Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

6 July 2018

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Cross talk between microRNA and epigenetic regulation in adult neurogenesis

6 July 2018

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A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay

6 July 2018

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Narrowing the boundaries of the genetic architecture of schizophrenia.

6 July 2018

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Recurrent reciprocal 16p11.2 rearrangements associated with global developmental delay, behavioural problems, dysmorphism, epilepsy, and abnormal head size

6 July 2018

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Microduplications of 16p11.2 are associated with schizophrenia

6 July 2018

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

6 July 2018

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Common variants on chromosome 6p22.1 are associated with schizophrenia

6 July 2018

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Common variants conferring risk of schizophrenia

6 July 2018

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Common genetic variation and human traits

6 July 2018

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Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

6 July 2018

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Population analysis of large copy number variants and hotspots of human genetic disease

6 July 2018

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Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

6 July 2018

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15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

6 July 2018

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Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities

6 July 2018

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A framework for interpreting genome-wide association studies of psychiatric disorders

6 July 2018

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Disruption of the neurexin 1 gene is associated with schizophrenia

6 July 2018

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Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes

6 July 2018

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Schizophrenia and sudden cardiac death: a review

6 July 2018

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Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

6 July 2018

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Large recurrent microdeletions associated with schizophrenia

6 July 2018

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Rare chromosomal deletions and duplications increase risk of schizophrenia

6 July 2018

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

6 July 2018

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Structural neuroimaging in psychosis: a systematic review and economic evaluation

6 July 2018

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Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

6 July 2018

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Structural variation of chromosomes in autism spectrum disorder

6 July 2018

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Association between microdeletion and microduplication at 16p11.2 and autism

6 July 2018

1 reference

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Recurrent 16p11.2 microdeletions in autism

6 July 2018

1 reference

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Strong association of de novo copy number mutations with autism

6 July 2018

1 reference

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Voltage-gated calcium channels in genetic diseases

6 July 2018

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Psychotic symptoms in children and adolescents with 22q11.2 deletion syndrome: Neuropsychological and behavioral implications

6 July 2018

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Schizophrenia and increased risks of cardiovascular disease

6 July 2018

1 reference

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Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory

6 July 2018

1 reference

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The Economic Burden of Schizophrenia in the United States in 2002

6 July 2018

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6 July 2018

12 December 2020

Antipsychotic drugs and QT prolongation

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Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes

6 July 2018

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A systematic review of the prevalence of schizophrenia

6 July 2018

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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

6 July 2018

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The global burden of typhoid fever

6 July 2018

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The International HapMap Project

6 July 2018

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

6 July 2018

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The molecular genetics of schizophrenia: new findings promise new insights

6 July 2018

1 reference

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Replication validity of genetic association studies

6 July 2018

1 reference

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Initial sequencing and analysis of the human genome

6 July 2018

1 reference

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Epidemiology of schizophrenia: the global burden of disease and disability

6 July 2018

1 reference

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Medical comorbidity in schizophrenia

6 July 2018

1 reference

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The future of genetic studies of complex human diseases

6 July 2018

1 reference

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Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study

6 July 2018

1 reference

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Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

6 July 2018

1 reference

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A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples

27 October 2018

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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

27 October 2018

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Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3809776

Epigenetics as a unifying principle in the aetiology of complex traits and diseases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3809776

Conditional forebrain deletion of the L-type calcium channel Ca V 1.2 disrupts remote spatial memories in mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3809776

Depression in chronic schizophrenia

27 October 2018

1 reference

PubMed

12 December 2020

Increased exonic de novo mutation rate in individuals with schizophrenia

1 reference

PubMed

12 December 2020

Excess mortality of mental disorder

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI66031

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24177465%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24177465%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24177465

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24177465%20AND%20SRC:MED&resulttype=core&format=json