Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins (Q34386755)

1 August 2017

title

Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins (English)

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1 August 2017

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Andre J van Wijnen

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1 August 2017

Gary S Stein

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1 August 2017

Jane B Lian

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1 August 2017

Janet L Stein

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1 August 2017

Jeffrey Nickerson

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1 August 2017

Karina Barseguian

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1 August 2017

Bart Lutterbach

series ordinal

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1 August 2017

Scott W Hiebert

series ordinal

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1 August 2017

language of work or name

English

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publication date

11 November 2002

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

15434-15439

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A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene

1 August 2017

cites work

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6 July 2018

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ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

6 July 2018

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Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.

6 July 2018

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6 July 2018

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

6 July 2018

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The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family.

6 July 2018

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The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

6 July 2018

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Characterization of the ETO and AML1-ETO proteins involved in 8;21 translocation in acute myelogenous leukemia

6 July 2018

1 reference

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Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Identification of YY1 sequences necessary for association with the nuclear matrix and for transcriptional repression functions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains

6 July 2018

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The AML1-MTG8 Leukemic Fusion Protein Forms a Complex with a Novel Member of the MTG8(ETO/CDR) Family, MTGR1

6 July 2018

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The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation

6 July 2018

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Differential Recognition of Liganded and Unliganded Thyroid Hormone Receptor by Retinoid X Receptor Regulates Transcriptional Repression

6 July 2018

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Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin

6 July 2018

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Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

6 July 2018

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Partial colocalization of glucocorticoid and mineralocorticoid receptors in discrete compartments in nuclei of rat hippocampus neurons

6 July 2018

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DEAF-1, a novel protein that binds an essential region in a Deformed response element

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

The ETO portion of acute myeloid leukemia t(8;21) fusion transcript encodes a highly evolutionarily conserved, putative transcription factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: The C-terminus is a principal determinant for nuclear trafficking

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.242588499

Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137734

Subnuclear partitioning and functional regulation of the Pit-1 transcription factor

27 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.242588499

Rat osteoblast and osteosarcoma nuclear matrix proteins bind with sequence specificity to the rat type I collagen promoter

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12427969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signal

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12427969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.242588499

1 reference

1 August 2017

0 references

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1 August 2017

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