KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation (Q34385576)

1 August 2017

title

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation (English)

1 reference

1 August 2017

Darell D Bigner

1 reference

1 August 2017

Roger E McLendon

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1 August 2017

Changcun Guo

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1 August 2017

Lee H Chen

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1 August 2017

Yafen Huang

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1 August 2017

Chun-Chi Chang

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1 August 2017

Ping Wang

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1 August 2017

Christopher J Pirozzi

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1 August 2017

Xiaoxia Qin

1 reference

1 August 2017

Xuhui Bao

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1 August 2017

Paula K Greer

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1 August 2017

Hai Yan

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1 August 2017

Stephen T Keir

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1 August 2017

Yiping He

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1 August 2017

language of work or name

English

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publication date

1 November 2013

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

2144-2153

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De novo mutations in histone-modifying genes in congenital heart disease.

1 August 2017

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6 July 2018

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Medulloblastoma or not? Crucial role in tumorigenesis of the timing of migration of cerebellar granule precursor cells, regulated by Nos2 and Tis21

6 July 2018

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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

6 July 2018

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Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4

6 July 2018

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Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neurons

6 July 2018

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Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways

6 July 2018

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Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

6 July 2018

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6 July 2018

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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

6 July 2018

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6 July 2018

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The mutational landscape of lethal castration-resistant prostate cancer

6 July 2018

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Novel mutations target distinct subgroups of medulloblastoma.

6 July 2018

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Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

6 July 2018

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Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing

6 July 2018

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Epigenomic enhancer profiling defines a signature of colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration

6 July 2018

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The pathogenesis of mixed-lineage leukemia

6 July 2018

1 reference

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Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer

6 July 2018

1 reference

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

6 July 2018

1 reference

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Analysis of the coding genome of diffuse large B-cell lymphoma

6 July 2018

1 reference

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

6 July 2018

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HOXC6 Is Transcriptionally Regulated via Coordination of MLL Histone Methylase and Estrogen Receptor in an Estrogen Environment

6 July 2018

1 reference

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Functional and Mechanistic Diversity of Distal Transcription Enhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

The genetic landscape of the childhood cancer medulloblastoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Model-based analysis of ChIP-Seq (MACS)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

The consensus coding sequences of human breast and colorectal cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875776

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24240169

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.1555

0 references

PMC publication ID

3875776

1 reference

1 August 2017

1 reference