Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein (Q34347265)

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English	Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Joseph Sodroski

10

object named as

Joseph Sodroski

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Europe PubMed Central

PubMed publication ID

1 August 2017

2

object named as

Peter D Kwong

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Europe PubMed Central

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1 August 2017

Richard T. Wyatt

6

object named as

Richard Wyatt

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1 August 2017

author name string

Shi-Hua Xiang

1

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1 August 2017

Rishi Gupta

3

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Europe PubMed Central

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1 August 2017

Carlo D Rizzuto

4

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Europe PubMed Central

PubMed publication ID

1 August 2017

David J Casper

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Liping Wang

7

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Wayne A Hendrickson

8

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Europe PubMed Central

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1 August 2017

Michael L Doyle

9

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Europe PubMed Central

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1 August 2017

language of work or name

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publication date

1 October 2002

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Europe PubMed Central

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1 August 2017

Journal of Virology

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1 August 2017

76

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Europe PubMed Central

PubMed publication ID

1 August 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

9888-9899

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

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A cavity-forming mutation in insulin induces segmental unfolding of a surrounding α-helix

1 reference

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

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6 July 2018

Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys

1 reference

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Stabilization of hen egg white lysozyme by a cavity-filling mutation

1 reference

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Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops

1 reference

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6 July 2018

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

1 reference

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6 July 2018

Association of structural changes in the V2 and V3 loops of the gp120 envelope glycoprotein with acquisition of neutralization resistance in a simian-human immunodeficiency virus passaged in vivo

1 reference

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Vaccines and immunology: elucidating immunity to HIV-1 and current prospects for AIDS vaccine development

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Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics

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Challenges in the development of an effective HIV vaccine: current approaches and future directions

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Energetics of the HIV gp120-CD4 binding reaction

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The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity

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Theoretical studies of the response of a protein structure to cavity-creating mutations.

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Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication

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The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution

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Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies

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The antigenic structure of the HIV gp120 envelope glycoprotein

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

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Why do we not have an HIV vaccine and how can we make one? .

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Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity

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The antibody response in HIV-1 infection.

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The V1/V2 Region of Human Immunodeficiency Virus Type 1 Modulates the Sensitivity to Neutralization by Soluble CD4 and Cellular Tropism

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Evaluating the energetics of empty cavities and internal mutations in proteins

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A vaccine for HIV type 1: The antibody perspective

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Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop

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Conformational Stabilities of Escherichia coli RNase HI Variants with a Series of Amino Acid Substitutions at a Cavity within the Hydrophobic Core

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HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor

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Dimeric association and segmental variability in the structure of human CD4

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Atomic structure of the ectodomain from HIV-1 gp41

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Core structure of gp41 from the HIV envelope glycoprotein

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Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

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The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection

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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

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The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

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Identification of a major co-receptor for primary isolates of HIV-1

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.

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Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities

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How to measure and predict the molar absorption coefficient of a protein

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

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Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.

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Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

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Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans

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Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer

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Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

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Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

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Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

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Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

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Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

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Receptor-mediated activation of immunodeficiency viruses in viral fusion

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Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

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Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120

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6 July 2018

Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody

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6 July 2018

An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection

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Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

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Analysis of the site in CD4 that binds to the HIV envelope glycoprotein.

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6 July 2018

Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region

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The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure

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6 July 2018

Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

6 July 2018

Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

6 July 2018

Progress in the development of an HIV-1 vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

27 October 2018

Properties of the protein matrix revealed by the free energy of cavity formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

27 October 2018

Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136507

27 October 2018

A single amino acid substitution can restore the solubility of aggregated colicin A mutants in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cavity-creating mutations on conformational stability and structure of the dimeric 4-alpha-helical protein ROP: thermal unfolding studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward an HIV type 1 vaccine that generates potent, broadly cross-reactive neutralizing antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability analysis for the cavity-filling mutations of the Myb DNA-binding domain utilizing free-energy calculations

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic analysis of cavity creating mutations in an engineered leucine zipper and energetics of glycerol-induced coiled coil stabilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filling a cavity dramatically increases pressure stability of the c-Myb R2 subdomain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of hydrophobic interactions to protein stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino-acid changes in HIV envelope affect viral tropism and receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.19.9888-9899.2002

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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