Genetic animal models: focus on schizophrenia (Q34338239)

1 August 2017

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title

Genetic animal models: focus on schizophrenia (English)

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1 August 2017

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1 August 2017

Caron MG

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1 August 2017

Mohn AR

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1 August 2017

publication date

1 September 2001

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1 August 2017

published in

Trends in Neurosciences

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

527-533

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Catching up on schizophrenia: natural history and neurobiology

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

To model a psychiatric disorder in animals: schizophrenia as a reality test

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dissection of behavior and psychiatric disorders using the mouse as a model

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Animal models for human PFC-related disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Animal models of human genetic diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

The Glutamatergic Dysfunction Hypothesis for Schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Schizophrenia and glutamatergic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine receptors and the dopamine hypothesis of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Increased baseline occupancy of D2 receptors by dopamine in schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Amphetamine: effects on catecholamine systems and behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Amphetamine psychosis: a "model" schizophrenia mediated by catecholamines

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Long-lasting psychotomimetic consequences of repeated low-dose amphetamine exposure in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Amphetamine psychosis and schizophrenia: a dual model

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Effects of continuous D-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Glutamate in CNS disorders as a target for drug development: an update

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Rodent data and general hypothesis: antipsychotic action exerted through 5-Ht2A receptor antagonism is dependent on increased serotonergic tone

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

The role of serotonin in antipsychotic drug action

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

PCP site 2: a high affinity MK-801-insensitive phencyclidine binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Profound neuronal plasticity in response to inactivation of the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis1Published on the World Wide Web on 27 January 1998.1

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Differential regulation of the dopamine D1, D2 and D3 receptor gene expression and changes in the phenotype of the striatal neurons in mice lacking the dopamine transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Loss of autoreceptor functions in mice lacking the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Functional hyperdopaminergia in dopamine transporter knock-out mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopaminergic role in stimulant-induced wakefulness.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

No evidence for linkage or association between the dopamine transporter gene and schizophrenia in a French population

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Genotypic association between dopamine transporter gene polymorphisms and schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

An animal model of attention deficit hyperactivity disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

New insights into dopaminergic receptor function using antisense and genetically altered animals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Topographical evaluation of the phenotype of spontaneous behaviour in mice with targeted gene deletion of the D1A dopamine receptor: paradoxical elevation of grooming syntax.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Mice Lacking Dopamine D4 Receptors Are Supersensitive to Ethanol, Cocaine, and Methamphetamine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Behavioural assessment of mice lacking D1A dopamine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Monoamine oxidase: from genes to behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Spatial learning deficit in dopamine D(1) receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Long-trace interval eyeblink conditioning is impaired in mutant mice lacking the NMDA receptor subunit epsilon 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

The molecular biology of serotonin receptors: therapeutic implications for the interface of mood and psychosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Enhanced cortical dopamine output and antipsychotic-like effects of raclopride by alpha2 adrenoceptor blockade

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

Social Interaction and Sensorimotor Gating Abnormalities in Mice Lacking Dvl1

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901886-5

7 January 2021

10.1016/S0166-2236(00)01886-5

Identifiers

DOI

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1 August 2017

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