Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver. (Q34329788)

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English	Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver.	scientific article

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PubMed publication ID

8024360

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23 October 2019

title

Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver (English)

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PubMed publication ID

8024360

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23 October 2019

author name string

S L Nyberg

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1

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8024360

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23 October 2019

R P Remmel

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2

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8024360

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23 October 2019

H J Mann

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3

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8024360

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8024360%20AND%20SRC:MED&resulttype=core&format=json

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23 October 2019

M V Peshwa

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4

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PubMed publication ID

8024360

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23 October 2019

W S Hu

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5

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PubMed publication ID

8024360

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23 October 2019

F B Cerra

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6

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PubMed publication ID

8024360

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23 October 2019

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English

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1 July 1994

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8024360

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23 October 2019

published in

Annals of Surgery

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8024360

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23 October 2019

volume

220

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8024360

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23 October 2019

issue

1

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PubMed publication ID

8024360

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23 October 2019

page(s)

59-67

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23 October 2019

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Liver assist devices (LADs) will not be used to treat fulminant hepatic failure (FHF), but its consequences, namely hepatic encephalopathy (HE)

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Induction of drug metabolizing enzymes in human liver cell line Hep G2

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HepG2. A human hepatoblastoma cell line exhibiting defects in bile acid synthesis and conjugation

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Drug metabolism by the human hepatoma cell, Hep G2

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Growth and hepatospecific gene expression of human hepatoma cells in a defined medium

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Overcoming retention time shifts as a source of error in HPLC analysis

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Induction and activity of several isoenzymes of cytochrome P-450 in primary cultures of rat hepatocytes, in comparison with in vivo data

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UDP-glucuronosyltransferases

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Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4.

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12 December 2020

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Metabolism of lidocaine by purified rat liver microsomal cytochrome P-450 isozymes

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12 December 2020

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Hep G2 cells as a resource for metabolic studies: lipoprotein, cholesterol, and bile acids

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12 December 2020

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Use of hepatocytes in adhesion and suspension cultures for liver support bioreactors

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Characterization of a transforming N-ras gene in the human hepatoma cell line Hep G2: additional evidence for the importance of c-myc and ras cooperation in hepatocarcinogenesis.

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Variation in drug-metabolizing enzyme activities during the growth of human Hep G2 hepatoma cells

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HepG2 cells: an in vitro model for P450-dependent metabolism of acetaminophen

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Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines

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Hepatocyte function in a hollow fiber bioreactor: a potential bioartificial liver

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Use of a novel bioartificial liver in a patient with acute liver insufficiency.

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Culturing of primary hepatocytes as entrapped aggregates in a packed bed bioreactor: a potential bioartificial liver

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Demonstration of biochemical function by extracorporeal xenohepatocytes in an anhepatic animal model

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Development of a hybrid bioartificial liver

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12 December 2020

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p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines

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12 December 2020

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Artificial liver: a forthcoming attraction

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12 December 2020

based on heuristic

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Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes

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PubMed

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12 December 2020

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Assessment of artificial liver support technology

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PubMed

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12 December 2020

based on heuristic

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Extracorporeal application of a gel-entrapment, bioartificial liver: demonstration of drug metabolism and other biochemical functions

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PubMed

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12 December 2020

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Long-term cultures of adult mammalian hepatocytes in hollow fibers as the cellular component of extracorporeal (hybrid) liver assist devices.

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed function oxidase and UDP-glucuronyltransferase activities in the human Hep G2 hepatoma cell line

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of culture medium composition on drug metabolising enzyme activities of the human liver derived Hep G2 cell line

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the liver specific phenotype in the human hepatoblastoma line Hep G2

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus-associated oncogenes

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12 December 2020

based on heuristic

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The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian hepatocytes as a foundation for treatment in human liver failure

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioartificial liver using hepatocytes on biosilon microcarriers: treatment of chemically induced acute hepatic failure in rats

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12 December 2020

based on heuristic

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A hybrid artificial liver system. Function of cultured monolayer pig hepatocytes in plasma from hepatic failure patients

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12 December 2020

based on heuristic

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Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of fulminant hepatic failure using an extracorporeal liver assist device

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variant protein patterns in hepatomas and transformed liver cell lines as determined by high resolution two-dimensional gel electrophoresis (2DE)

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection of variant hepatoma cells in liver-specific growth media: regulation at the mRNA level

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte culture systems for artificial liver support: implications for critical care medicine (bioartificial liver support).

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoprotection of xenocytes in a hollow fiber bioartificial liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does a porcine hepatocyte hybrid artificial liver prolong the survival time of anhepatic rabbits?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved liver function following treatment with an extracorporeal liver assist device

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

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Chapter 4 Preparation of Isolated Rat Liver Cells

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https://pubmed.ncbi.nlm.nih.gov/8024360

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12 December 2020

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PubMed publication ID

8024360

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Europe PubMed Central

PubMed publication ID

8024360

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8024360%20AND%20SRC:MED&resulttype=core&format=json

retrieved

23 October 2019

 

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