Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5 (Q34325074)

1 August 2017

title

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5 (English)

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1 August 2017

Carl H June

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1 August 2017

Bruce L Levine

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1 August 2017

Dawn A Maier

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1 August 2017

Andrea L Brennan

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1 August 2017

Shuguang Jiang

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1 August 2017

Gwendolyn K Binder-Scholl

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1 August 2017

Gary Lee

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1 August 2017

Gabriela Plesa

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1 August 2017

Zhaohui Zheng

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1 August 2017

Julio Cotte

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1 August 2017

Carmine Carpenito

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1 August 2017

Travis Wood

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1 August 2017

S Kaye Spratt

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1 August 2017

Dale Ando

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1 August 2017

Philip Gregory

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1 August 2017

Michael C Holmes

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1 August 2017

Elena E Perez

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1 August 2017

James L Riley

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1 August 2017

Richard G Carroll

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1 August 2017

publication date

6 March 2013

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

245-258

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An unbiased genome-wide analysis of zinc-finger nuclease specificity

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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In vitro induction of carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses

6 July 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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28 October 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Highly altered V beta repertoire of T cells infiltrating long-term rejected kidney allografts.

6 July 2018

1 reference

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6 July 2018

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A detailed study of the substrate specificity of a chimeric restriction enzyme.

6 July 2018

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Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors

6 July 2018

1 reference

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Development of antibodies to fetal calf serum with arthus-like reactions in human immunodeficiency virus-infected patients given syngeneic lymphocyte infusions.

6 July 2018

1 reference

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Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure

6 July 2018

1 reference

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Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

6 July 2018

1 reference

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Gene therapy: a bold direction for HIV-1 treatment

6 July 2018

1 reference

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T-cell repertoire diversity and clonal expansions in normal and clinical samples

6 July 2018

1 reference

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EBV-induced human B cell lymphomas in hu-PBL-SCID mice

6 July 2018

1 reference

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A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation.

6 July 2018

1 reference

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Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer.

28 October 2018

1 reference

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Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

28 October 2018

1 reference

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28 October 2018

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28 October 2018

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Molecular remission of CML after autotransplantation followed by adoptive transfer of costimulated autologous T cells

28 October 2018

1 reference

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Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

Immune response to fetal calf serum by two adenosine deaminase-deficient patients after T cell gene therapy

28 October 2018

1 reference

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Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.

28 October 2018

1 reference

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Direct recognition of foreign MHC determinants by naive T cells mobilizes specific Vbeta families without skewing of the complementarity-determining region 3 length distribution.

28 October 2018

1 reference

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Longitudinal changes in CD4+ T cell antigen receptor diversity and naive/memory cell phenotype during 9 to 26 months of antiretroviral therapy of HIV-infected patients.

28 October 2018

1 reference

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Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

Progression of human immunodeficiency virus disease is associated with increasing disruptions within the CD4+ T cell receptor repertoire

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609630

Efficient clinical-scale enrichment of lymphocytes for use in adoptive immunotherapy using a modified counterflow centrifugal elutriation program

28 October 2018

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12 December 2020

Allogeneic transplantation of CCR5-deficient progenitor cells in a patient with HIV infection: an update after 3 years and the search for patient no. 2

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12 December 2020

Blocking HIV's attack

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12 December 2020

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

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12 December 2020

CD28 ligands CD80 (B7-1) and CD86 (B7-2) induce long-term autocrine growth of CD4+ T cells and induce similar patterns of cytokine secretion in vitro

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12 December 2020

Limits of the human-PBL-SCID mice model: severe restriction of the V beta T-cell repertoire of engrafted human T cells

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12 December 2020

Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals

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12 December 2020

CCR2 chemokine receptor and AIDS progression

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12 December 2020

Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy

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12 December 2020

Large-scale production of CD4+ T cells from HIV-1-infected donors after CD3/CD28 costimulation

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12 December 2020

Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy

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12 December 2020

Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human peptide-pulsed dendritic cells

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12 December 2020

Different qualitative and quantitative regulation of V beta TCR transcripts during early acute allograft rejection and tolerance induction

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12 December 2020

Duplex polymerase chain reaction quantification of human cells in a murine background

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12 December 2020

Evaluation of TCR Vbeta subfamily T cell expansion in NOD/SCID mice transplanted with human cord blood hematopoietic stem cells

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12 December 2020

Identifiers

DOI

10.1089/HUM.2012.172

1 reference

1 August 2017

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1 August 2017

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