Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways. (Q34317872)

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English	Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways.	scientific article

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20 February 2020

Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways (English)

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20 February 2020

Toxoplasma gondii

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5

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20 February 2020

Zurine De Miguel

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20 February 2020

Robert Sapolsky

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Robert M Sapolsky

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20 February 2020

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I-Ping Lee

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20 February 2020

Andrew K Evans

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20 February 2020

Cissy Yang

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20 February 2020

Melissa G Works

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20 February 2020

Nathan C Manley

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20 February 2020

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9 October 2014

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20 February 2020

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20 February 2020

9

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20 February 2020

10

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20 February 2020

e109803

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20 February 2020

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Creative Commons Attribution 4.0 International

9 October 2014

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Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression.

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The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp

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GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii

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6 July 2018

Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii.

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A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins

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Roles of glutamine in neurotransmission.

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6 July 2018

SNAT2 transceptor signalling via mTOR: a role in cell growth and proliferation?

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Modelling parasite dissemination: host cell subversion and immune evasion by Toxoplasma gondii.

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Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions

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6 July 2018

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

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6 July 2018

The Toxoplasma gondii-shuttling function of dendritic cells is linked to the parasite genotype.

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6 July 2018

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

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6 July 2018

Phosphoinositide 3-kinases in cell migration

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6 July 2018

Inhibition of SNAT2 by metabolic acidosis enhances proteolysis in skeletal muscle

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6 July 2018

Kiss and spit: the dual roles of Toxoplasma rhoptries

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6 July 2018

Exogenous glutamine--compensating a shortage?

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6 July 2018

Glutamine concentration and immune response of spinal cord-injured rats.

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6 July 2018

Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors

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6 July 2018

Amino acids and immune function

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6 July 2018

The Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4.

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6 July 2018

Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.

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6 July 2018

Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction

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6 July 2018

Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host

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Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors

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6 July 2018

Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains.

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Upstream and downstream of mTOR

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6 July 2018

Genetic analysis of the diversity in Toxoplasma gondii.

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Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

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Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?

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The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression

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Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination

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21 January 2018

Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation

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21 January 2018

Glutamate is the chemotaxis-inducing factor in placental extracts

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21 January 2018

Glutamate induces neutrophil cell migration by activating class I metabotropic glutamate receptors.

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Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4.

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21 January 2018

A synthetic peptide derived from the parasite Toxoplasma gondii triggers human dendritic cells' migration.

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21 January 2018

Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells

1 reference

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12 December 2020

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Stromal progenitor cells promote leukocyte migration through production of stromal-derived growth factor 1alpha: a potential mechanism for stromal progenitor cell-mediated enhancement of cellular recruitment to wounds

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https://pubmed.ncbi.nlm.nih.gov/25299045

12 December 2020

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10.1371/JOURNAL.PONE.0109803

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20 February 2020

2014PLoSO...9j9803L

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20 February 2020

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20 February 2020

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