Mutant hepatitis B viruses: a matter of academic interest only or a problem with far-reaching implications? (Q34293921)

1 August 2017

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title

Mutant hepatitis B viruses: a matter of academic interest only or a problem with far-reaching implications? (English)

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1 August 2017

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François G

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1 August 2017

Kew M

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1 August 2017

Van Damme P

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1 August 2017

Mphahlele MJ

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1 August 2017

Meheus A

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1 August 2017

language of work or name

English

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publication date

1 July 2001

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1 August 2017

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1 August 2017

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1 August 2017

issue

28-29

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1 August 2017

page(s)

3799-3815

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More than third of world's population has been infected with hepatitis B virus

1 August 2017

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Recombinant versus plasma-derived hepatitis B vaccines: issues of safety, immunogenicity and cost-effectiveness

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7 January 2021

Development and production aspects of a recombinant yeast-derived hepatitis B vaccine

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7 January 2021

Pediatric experience with recombinant hepatitis B vaccines and relevant safety and immunogenicity studies

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7 January 2021

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7 January 2021

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7 January 2021

Loss of the common "A" determinant of hepatitis B surface antigen by a vaccine-induced escape mutant

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7 January 2021

The prevalence of surface antigen variants of hepatitis B virus in Papua New Guinea, South Africa, and Sardinia

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7 January 2021

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7 January 2021

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7 January 2021

Concentrating missense mutations in core gene of hepatitis B virus. Evidence for adaptive mutation in chronic hepatitis B virus infection

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7 January 2021

Pathogenesis of posttransfusion viral hepatitis in children with β-thalassemia

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7 January 2021

Frequency of hepatitis B virus e-minus mutants varies among patients from different areas of China

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7 January 2021

Viral dynamics in hepatitis B virus infection

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7 January 2021

The role of pre-core hepatitis B virus mutants on the long-term outcome of chronic hepatitis B virus hepatitis. A longitudinal study

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants

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7 January 2021

Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal

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7 January 2021

The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees

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7 January 2021

A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis B.

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7 January 2021

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7 January 2021

Precore wild-type DNA and immune complexes persist in chronic hepatitis B after seroconversion: No association between genome conversion and seroconversion

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7 January 2021

Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States

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7 January 2021

Variations of hepatitis B virus precore/core gene sequence in acute and fulminant hepatitis B.

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7 January 2021

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7 January 2021

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7 January 2021

Accumulation and persistence of hepatitis B virus core gene deletion mutants in renal transplant patients are associated with end-stage liver disease

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7 January 2021

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7 January 2021

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Hepatitis B virus surface mutations associated with infection after liver transplantation

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7 January 2021

Glycine-to-arginine substitution at codon 145 of HBsAg in two infants born to hepatitis B e antigen-positive carrier

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

The hepatitis B virus seroconversion to anti-HBe is frequently associated with HBV genotype changes and selection of preS2-defective particles in chronically infected children

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7 January 2021

Hepatitis B defective virus with rearrangements in the preS gene during chronic HBV infection

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7 January 2021

A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA.

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7 January 2021

Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors

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7 January 2021

Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine

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7 January 2021

Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy

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7 January 2021

Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance

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7 January 2021

The sequential occurrence of viral mutations in a liver transplant recipient re-infected with hepatitis B: hepatitis B immune globulin escape, famciclovir non-response, followed by lamivudine resistance resulting in graft loss.

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7 January 2021

Naturally occurring missense mutation in the polymerase gene terminating hepatitis B virus replication

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7 January 2021

Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors

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7 January 2021

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

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7 January 2021

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

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7 January 2021

Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues

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7 January 2021

HBxAg in the liver from carrier patients with chronic hepatitis and cirrhosis

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7 January 2021

Detection of a hepatitis B virus variant with a truncated X gene and enhancer II.

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7 January 2021

Complete nucleotide sequences and the characteristics of two hepatitis B virus mutants causing serologically negative acute or chronic hepatitis B.

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7 January 2021

Hepatitis B virus with X gene mutation is associated with the majority of serologically "silent" non-b, non-c chronic hepatitis

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7 January 2021

Replication of a mutant hepatitis B virus with a fused X-C reading frame in hepatoma cells

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7 January 2021

The core promoter of hepatitis B virus

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7 January 2021

Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) --> T, A(1762) --> T and G(1764) --> A mutations in the core promoter

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7 January 2021

Hepatitis B virus X gene 1751 to 1764 mutations: implications for HBeAg status and disease

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7 January 2021

Chasing the escape mutant

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7 January 2021

Molecular variants of hepatitis B virus.

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7 January 2021

Hepatitis B: Diagnosis and Treatment

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7 January 2021

Mechanisms of immune escape in viral hepatitis

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7 January 2021

Subversion of the immune system by pathogens.

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7 January 2021

Resistance of human immunodeficiency virus type 1 to neutralization by natural antisera occurs through single amino acid substitutions that cause changes in antibody binding at multiple sites

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7 January 2021

Hepatitis B virus immunopathology

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7 January 2021

Hepatitis B virus core protein mutations are concentrated in B cell epitopes in progressive disease and in T helper cell epitopes during clinical remission

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7 January 2021

Disquisitions of Original Antigenic Sin. I. Evidence in man

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7 January 2021

Disquisitions on Original Antigenic Sin. II. Proof in lower creatures

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7 January 2021

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes

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7 January 2021

Role of preimmunization virus sequences in cellular immunity in HIV-infected patients during HIV type 1 MN recombinant gp160 immunization

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7 January 2021

Analysis of the original antigenic sin antibody response to the major outer membrane protein of Chlamydia trachomatis

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7 January 2021

Selective recognition of malaria antigens by human serum antibodies is not genetically determined but demonstrates some features of clonal imprinting

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7 January 2021

Heterogeneity of hepatitis B virus C-gene sequences: implications for amplification and sequencing

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7 January 2021

Trans-complementation among naturally occurring deletion mutants of hepatitis B virus and integrated viral DNA for the production of viral particles with mutant genomes in hepatoma cell lines

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7 January 2021

A novel deletion mutant of hepatitis B virus surface antigen.

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7 January 2021

Identification of hepatitis B surface antigen variants with alterations outside the "a" determinant in immunized Singapore infants

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7 January 2021

Independent emergence of a vaccine-induced escape mutant of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Low Detection Rate and Maternal Provenance of Hepatitis B Virus S Gene Mutants in Cases of Failed Postnatal Immunoprophylaxis in England and Wales

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

The predicted pattern of emergence of vaccine-resistant hepatitis B: a cause for concern?

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Hepatitis B virus mutants and efficacy of vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Enhanced immunogenicity of the pre-S region of hepatitis B surface antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Safety and immunogenicity of a novel mammalian cell-derived recombinant hepatitis B vaccine containing Pre-S1 and Pre-S2 antigens in children

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

A comparative trial of standard or high-dose S subunit recombinant hepatitis B vaccine versus a vaccine containing S subunit, pre-S1, and pre-S2 particles for revaccination of healthy adult nonresponders

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Immune response to a new hepatitis B vaccine in healthcare workers who had not responded to standard vaccine: randomised double blind dose-response study

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Hepatitis B third-generation vaccines: improved response and conventional vaccine non-response--evidence for genetic basis in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Human leukocyte antigens influence the immune response to a pre-S/S hepatitis B vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

The influence of host factors and immunogenetics on lymphocyte responses to HepageneS vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Current status of HBV vaccine escape variants--a mathematical model of their epidemiology

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

The transmission dynamics and control of hepatitis B virus in The Gambia

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Vaccination, evolution and changes in the efficacy of vaccines: a theoretical framework.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

New hepatitis B virus mutant form in a blood donor that is undetectable in several hepatitis B surface antigen screening assays

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Gene therapy for chronic viral hepatitis: ribozymes, antisense oligonucleotides, and dominant negative mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Observations on constitutional resistance to infection

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

A high-stakes gamble on genome sequencing.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Human Genome Project. Sequencers endorse plan for a draft in 1 year

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

The human genome project and the future of diagnostics, treatment, and prevention

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

Mining the genome for drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2801%2900108-6

7 January 2021

10.1016/S0264-410X(01)00108-6

Identifiers

DOI

1 reference

1 August 2017

1 reference