New agents in cancer clinical trials (Q34293629)

1 August 2017

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title

New agents in cancer clinical trials (English)

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1 August 2017

J Adams

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1 August 2017

P J Elliott

series ordinal

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1 August 2017

language of work or name

English

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publication date

1 December 2000

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

6687-6692

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Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Distamycins inhibit the binding of OTF-1 and NFE-1 transfactors to their conserved DNA elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Transit of pp60v-src to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Characterisation of antimitotic products from marine organisms that disorganise the microtubule network: ecteinascidin 743, isohomohalichondrin-B and LL-15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Three proteins define a class of human histone deacetylases related to yeast Hda1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Antitumor effects due to irreversible stoppage of tumor tissue blood flow: evaluation of a novel combretastatin A-4 derivative, AC7700.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Apicidin, an inhibitor of histone deacetylase, prevents H-ras-induced invasive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Histone acetylases and deacetylases in cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

A novel combretastatin A-4 derivative, AC-7700, shows marked antitumor activity against advanced solid tumors and orthotopically transplanted tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Phase I study of (6R)-5,10-dideazatetrahydrofolate: a folate antimetabolite inhibitory to de novo purine synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

The ubiquitin-proteasome pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Whole-body disposition and polyglutamate distribution of the GAR formyltransferase inhibitors LY309887 and lometrexol in mice: effect of low-folate diet

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

A New, More Efficient, and Effective Process for the Synthesis of a Key Pentacyclic Intermediate for Production of Ecteinascidin and Phthalascidin Antitumor Agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Ecteinascidins 729, 743, 745, 759A, 759B, and 770: potent antitumor agents from the Caribbean tunicate Ecteinascidia turbinata

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204088

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204088

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Dimensions Publication ID

1 August 2017

1035135661

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