Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment (Q34293595)

1 August 2017

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title

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment (English)

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1 August 2017

Zucker S

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1 August 2017

Cao J

series ordinal

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1 August 2017

Chen WT

series ordinal

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1 August 2017

language of work or name

English

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publication date

1 December 2000

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

6642-6650

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A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1 August 2017

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Proteolytic remodeling of extracellular matrix

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Matrix metalloproteinases: a review

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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Changing views of the role of matrix metalloproteinases in metastasis

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Matrix metalloproteinases in tumour invasion and metastasis

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Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases

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Activity of type IV collagenases in benign and malignant breast disease

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Protease inhibitors: role and potential therapeutic use in human cancer

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Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

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Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

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Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

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Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor

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In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1.

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Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: implications for angiogenesis

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Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins

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MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

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Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release

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Matrix metalloproteinases

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Matrix metalloproteinases in inflammatory demyelination: targets for treatment

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Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.

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Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain

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Molecular bases of the acute coronary syndromes

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Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid

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7 January 2021

Bacterial exposure induces and activates matrilysin in mucosal epithelial cells

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Matrix metalloproteinases: multifunctional contributors to tumor progression

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7 January 2021

Matrix metalloproteinases

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Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

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7 January 2021

Matrix metalloproteinases: biologic activity and clinical implications

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7 January 2021

Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

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7 January 2021

High affinity binding of latent matrix metalloproteinase-9 to the alpha2(IV) chain of collagen IV.

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7 January 2021

Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity

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7 January 2021

Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers

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The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

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7 January 2021

Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

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7 January 2021

A matrix metalloproteinase expressed on the surface of invasive tumour cells

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7 January 2021

Antitumor efficacy of AG3340 associated with maintenance of minimum effective plasma concentrations and not total daily dose, exposure or peak plasma concentrations

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7 January 2021

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

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7 January 2021

Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic

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7 January 2021

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

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7 January 2021

Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members

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7 January 2021

Matrix metalloproteinase inhibitors

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7 January 2021

Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7)

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7 January 2021

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

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7 January 2021

Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: not an invariant correlation with metastasis

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7 January 2021

Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation

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7 January 2021

Guidelines for clinical trial design for evaluation of MMP inhibitors

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204097

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Dimensions Publication ID

1 August 2017

1050913107

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