Development of a Bacillus subtilis-based rotavirus vaccine (Q34289936)

1 August 2017

title

Development of a Bacillus subtilis-based rotavirus vaccine (English)

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1 August 2017

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Saul Tzipori

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1 August 2017

Sangun Lee

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1 August 2017

Boris R Belitsky

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1 August 2017

James P Brinker

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1 August 2017

Kathryn O Kerstein

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1 August 2017

David W Brown

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1 August 2017

John D Clements

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1 August 2017

Gerald T Keusch

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1 August 2017

Abraham L Sonenshein

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1 August 2017

John E Herrmann

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1 August 2017

publication date

1 September 2010

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Clinical and Vaccine Immunology

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

1647-1655

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Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin

1 August 2017

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6 July 2018

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6 July 2018

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Safety and immunogenicity of two live attenuated human rotavirus vaccine candidates, 116E and I321, in infants: results of a randomised controlled trial.

6 July 2018

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6 July 2018

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CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).

6 July 2018

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6 July 2018

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6 July 2018

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Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs

6 July 2018

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Resistance of Bacillus endospores to extreme terrestrial and extraterrestrial environments

6 July 2018

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Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein.

6 July 2018

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Role and regulation of Bacillus subtilis glutamate dehydrogenase genes

6 July 2018

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Subunit rotavirus vaccine administered parenterally to rabbits induces active protective immunity

6 July 2018

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Antibody-Secreting Cell Responses and Protective Immunity Assessed in Gnotobiotic Pigs Inoculated Orally or Intramuscularly with Inactivated Human Rotavirus

6 July 2018

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Evidence that resolution of rotavirus infection in mice is due to both CD4 and CD8 cell-dependent activities

6 July 2018

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Rotavirus virus-like particles administered mucosally induce protective immunity

6 July 2018

1 reference

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Deletion of the Bacillus subtilis isocitrate dehydrogenase gene causes a block at stage I of sporulation

6 July 2018

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A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens

6 July 2018

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CD8+ T cells can mediate almost complete short-term and partial long-term immunity to rotavirus in mice.

6 July 2018

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6 July 2018

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Immunogenicity, safety and efficacy of tetravalent rhesus-human, reassortant rotavirus vaccine in Belém, Brazil.

6 July 2018

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Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon.

6 July 2018

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Rotavirus vaccine administered parenterally induces protective immunity

6 July 2018

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Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity

6 July 2018

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Use of the Escherichia coli lac repressor and operator to control gene expression in Bacillus subtilis

6 July 2018

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6 July 2018

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The role of helper T cell products in mouse B cell differentiation and isotype regulation

6 July 2018

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Identification and characterization of genes controlled by the sporulation-regulatory gene spo0H in Bacillus subtilis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

A target for carbon source-dependent negative regulation of the citB promoter of Bacillus subtilis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Recovery from chronic rotavirus infection in mice with severe combined immunodeficiency: virus clearance mediated by adoptive transfer of immune CD8+ T lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

A dose-escalation safety and immunogenicity study of live attenuated oral rotavirus vaccine 116E in infants: a randomized, double-blind, placebo-controlled trial

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Enhanced immunisation and expression strategies using bacterial spores as heat-stable vaccine delivery vehicles.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Protection against rotavirus shedding after intranasal immunization of mice with a chimeric VP6 protein does not require intestinal IgA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Distribution and phenotype of murine rotavirus-specific B cells induced by intranasal immunization with 2/6 virus-like particles

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

New shuttle vectors for ectopic insertion of genes into Bacillus subtilis

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Bacterial expression of the major antigenic regions of porcine rotavirus VP7 induces a neutralizing immune response in mice

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976104

Efficacy of the Rhesus Rotavirus–Based Quadrivalent Vaccine in Infants and Young Children in Venezuela

28 October 2018

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12 December 2020

Immune responses and protection obtained by oral immunization with rotavirus VP4 and VP7 DNA vaccines encapsulated in microparticles

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12 December 2020

Immune response to rotavirus VP4 expressed in an attenuated strain of Shigella flexneri

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12 December 2020

Effect of oral rotavirus/iscom vaccines on immune responses in gnotobiotic lambs

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Rotavirus vp7 antigen produced by Lactococcus lactis induces neutralizing antibodies in mice

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Evaluation of different promoter sequences and antigen sorting signals on the immunogenicity of Bacillus subtilis vaccine vehicles

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On the fate of ingested Bacillus spores

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Immune responses and protection obtained with rotavirus VP6 DNA vaccines given by intramuscular injection

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Safety, Immunogenicity, and Protective Efficacy of One and Three Doses of the Tetravalent Rhesus Rotavirus Vaccine in Infants in Lima, Peru

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Protection against rotavirus infections by DNA vaccination

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Differential production of IL-12 in BALB/c and DBA/2 mice controls IL-4 versus IFN-gamma synthesis in primed CD4 lymphocytes

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Identifiers

DOI

10.1128/CVI.00135-10

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1 August 2017

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1 August 2017

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