Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. (Q34288205)

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7 February 2020

title

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155 (English)

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7 February 2020

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7 February 2020

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7 February 2020

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7 February 2020

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7 February 2020

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7 February 2020

S Mattiske

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7 February 2020

C P Bracken

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7 February 2020

R B Schulz

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7 February 2020

S P Lim

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7 February 2020

R Kumar

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7 February 2020

R J Suetani

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7 February 2020

language of work or name

English

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publication date

16 July 2012

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7 February 2020

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7 February 2020

volume

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7 February 2020

issue

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7 February 2020

page(s)

2992-3000

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Mutant p53 gain-of-function in cancer

7 February 2020

cites work

1 reference

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The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

21 January 2018

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Mutant p53 drives invasion by promoting integrin recycling

21 January 2018

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

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Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

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MicroRNA gene expression deregulation in human breast cancer

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MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene

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Epithelial mesenchymal transition traits in human breast cancer cell lines.

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Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

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p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.

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Genes that mediate breast cancer metastasis to lung

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ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription

21 January 2018

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CBFA2T3-ZNF652 corepressor complex regulates transcription of the E-box gene HEB.

21 January 2018

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MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways

21 January 2018

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Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

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The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells.

21 January 2018

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Lamellipodia and filopodia in metastasis and invasion

21 January 2018

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MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer

21 January 2018

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MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA

21 January 2018

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miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT

21 January 2018

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Programmed cell death 4 inhibits breast cancer cell invasion by increasing tissue inhibitor of metalloproteinases-2 expression

21 January 2018

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Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion

21 January 2018

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A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

21 January 2018

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Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition

21 January 2018

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Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

21 January 2018

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Transforming growth factor-beta facilitates breast carcinoma metastasis by promoting tumor cell survival

21 January 2018

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TGF-beta signaling in cancer--a double-edged sword

21 January 2018

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Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.

21 January 2018

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A peptidomimetic siRNA transfection reagent for highly effective gene silencing.

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Nutlin-3a is a potential therapeutic for ewing sarcoma

21 January 2018

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

21 January 2018

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When mutants gain new powers: news from the mutant p53 field.

21 January 2018

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Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

31 March 2020

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p53 alterations in all stages of breast cancer

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2012.305

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22797073%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 February 2020

1048875330

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22797073%20AND%20SRC:MED&resulttype=core&format=json